Kauran-16,17-diol (ent-Kauran-16β,17-diol) 是一个天然的二萜化合物,具有抗肿瘤诱导凋亡的活性。其抑制 LPS 诱导的RAW 264.7 细胞产生 NO 皃b>IC
50值为17 μM、/div>
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Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with aIC50of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages[1][2].
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体外研究 (In Vitro) |
Kauran-16,17-diol (ent-Kauran-16β,17-diol) down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells[1].
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| 来源 |
- Plants
- Liliaceae
- Fritillaria cirrhosa
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis.
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