靶标９�p style="text-indent: 2em;">CYP2C18

产品别名９�p style="text-indent: 2em;">CPCI� CYP2C� CYP2C17� P450-6B/29C� P450IIC17� CYP2C18� cytochrome P450 family 2 subfamily C member 18� cytochrome P450 family 2 subfamily C member 18� cytochrome P450 2C18� (S)-mephenytoin hydroxylase associated cytochrome P450� CYPIIC18� cytochrome P450, family 2, subfamily C, polypeptide 18� cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17� cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18� cytochrome P450-6B/29C� flavoprotein-linked monooxygenase� microsomal monooxygenase� unspecific monooxygenase� 细胞色素P450 2C18�

背景信息９�div style="text-indent: 2em;">This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],