靶标９�p style="text-indent: 2em;">CTNND2

产品别名９�p style="text-indent: 2em;">GT24� NPRAP� CTNND2� catenin delta 2� catenin delta 2� catenin delta-2� T-cell delta-catenin� catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)� neurojungin� δ-连环蛋白�

背景信息９�div style="text-indent: 2em;">catenin delta 2(CTNND2) Homo sapiens This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],