Manganese(IV) oxide

MnO₂

86.94

MFCD00003463

215-202-6

Manganese(IV) oxide (MnO₂) can be used as an oxidizing agent for the oxidation of:

• Allylic alcohols to α, β-ethylenic aldehydes, or ketones.
• Propargylic alcohols to alkynic aldehydes or ketones.
• Benzylic and heterocyclic alcohols to conjugated aromatic aldehydes or ketones.
• Amines to aldehydes, imines, amides, and diazo compounds. Methyl arenes to form primary amides in the presence of urea and oxygen.
• MnO₂ can also be used to synthesize disubstituted oxazolines from aldoximes via in situ nitrile oxide formation. Non-activated cyclic and acyclic alcohols oxidized to ketone analogs using stoichiometric MnO₂ and a ruthenium catalyst.

Assay (iodometric, calc. on dried substance): ≥ 90.0 %
Loss on drying: ≤ 3.5 %
Oxidation Activity: passes test

200

powder

>3478 mg/kg LD₅₀, oral (Rat)

reagent type: oxidant

insoluble <0.001 g/L

5.21 g/cm³ at 21 ℃

600‑800 kg/m³

2-30℃

1S/Mn.2O

NUJOXMJBOLGQSY-UHFFFAOYSA-N

GHS07,GHS08

Warning

H302 + H332 - H373

P260 - P264 - P270 - P301 + P312 - P304 + P340 + P312 - P314

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 2 Inhalation

Brain

13 - Non Combustible Solids

WGK 1