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Anti-FADD (AB2) antibody produced in rabbit
| 半岛bd体育手机客户端 编号： | 3361066 |
| 规格： | affinity isolated antibody |
| 包装规格： | 100 μL |
| 半岛bd体育手机客户端 类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
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别名
Anti-FADD (AB2) antibody produced in rabbit
Anti-Fas (TNFRSF6)-associated via death domain
Anti-Mort1/FADD
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | FADD is a death domain-containing protein that associates with fas and mediates apoptosis. Rabbit Anti-FADD (AB2) antibody binds to mouse FADD. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of mouse FADD |
| Application【应用】 | Rabbit Anti-FADD (AB2) antibody is suitable for use in western blot (0.25μg/ml) assays. |
| Biochem/physiol Actions【生化/生理作用】 | Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. |
| Sequence【序列】 | Synthetic peptide located within the following region: ASVAGLVKALRTCRLNLVADLVEEAQESVSKSENMSPVLRDSTVSSSETP |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 23 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_034305 |
| UniProt accession no.【UniProt登记号】 | Q61160 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Fadd(14082) |
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说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
