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YZ9
半岛bd体育手机客户端
价格查看更多规格...
| 半岛bd体育手机客户端 编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3260754 | 10 MG | 1220 |
半岛bd体育手机客户端
别名
6093-71-6
YZ9
7-hydroxy-2-oxo-2H-1-benzopyran-3-carboxylic acid ethyl ester
3-Carbethoxy-7-hydroxycoumarin
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H10O5 |
| Molecular weight | 234.20 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | YZ9 is a potent inhibitor of PFKFB3 (6-phosphfructo-2-kinase/fructose-2,6-bisphosphatase) with an IC50 = 183 nM. PFKFB3 is over expressed in many cancers and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YZ9 dose dependently inhibits proliferation of HeLa cells. YZ9 is a 5, 6, 7, 8-tetrahydroxy-2-(4-hydroxyphenyl) chromen-4-one (N4A) inhibitor. |
半岛bd体育手机客户端
性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 5 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C12H10O5/c1-2-16-11(14)9-5-7-3-4-8(13)6-10(7)17-12(9)15/h3-6,13H,2H2,1H3 |
| InChI key | IETDBZQIWIJQJG-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
