基因名：

TMA16

产品别名９�p style="text-indent: 2em;">C4orf43� TMA16� translation machinery associated 16 homolog� translation machinery associated 16 homolog� translation machinery-associated protein 16� UPF0534 protein C4orf43� 4号染色体开放阅读框43/FLJ11184�

背景信息９�div style="text-indent: 2em;">Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. The FLJ11184 gene product has been provisionally designated FLJ11184 pending further characterization.