基因名：

Dusp18

产品别名９�p style="text-indent: 2em;">4930527G07Rik� AI430870� BB028064� DSP18� DUSP20� LMWDSP20� Dusp18� dual specificity phosphatase 18� dual specificity phosphatase 18� dual specificity protein phosphatase 18� low molecular weight dual specificity phosphatase 20� 双特异性磷酸酶18�

背景信息９�div style="text-indent: 2em;">Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]