靶标９�p style="text-indent: 2em;">MGAT2

产品别名９�p style="text-indent: 2em;">CDG2A� CDGS2� GLCNACTII� GNT-II� GNT2� MGAT2� alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase� alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase� alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase� Beta-1,2-N-acetylglucosaminyltransferase II� N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II� UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II� glcNAc-T II� mannoside acetylglucosaminyltransferase 2� mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase�

背景信息９�div style="text-indent: 2em;">The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.