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?Achieve the most comprehensive coverage of coding regions: Coverage of genes from RefSeq RefGene CDS, CCDS, and miRBase v14 databases, plus coverage of 97% Vega, 97% Gencode, and 99% Ensembl databases.
?Experience the highest target enrichment efficiency: The NimbleGen Sequence Capture advanced design algorithm coupled with 2.1 million long oligonucleotide probes delivers superior target enrichment performance to discover more variants, including both single nucleotide variants and indels. See Nature Biotechnology article for a detailed comparison of target enrichment methods.
?Maximize variant discovery while minimizing sequencing costs: Reduce the sequencing output needed to verify mutations potentially responsible for disease.