产品介绍
| 目录叶br/>Serial |
TCHu228 |
| 标识?br/>Identifier |
CSTR:19375.09.3101HUMTCHu228 |
描述
Description |
NIH-OVCAR-3细胞由T.C.Hamilton?982年建系 取材于患进行性卵巢腺癌病人的恶性腹水 ?07细胞联合皮下接种５只裸鼠21天后全部成瘤 NIH-OVCAR-3是研究卵巢癌药物抗性的一个合适的模型系统且由于存在激素受体，这对于激素治疗的评估或许是有用的、br/>预定此细胞需至少提前两周、br/>在本库通过支原体检测、br/>在本库通过STR检测、/span> |
动物种别
Organism |
亹/span> |
性别
Gender |
奲/span> |
组织来源
Tissue and Cell Type |
器官：卵巢疾病：腺癌细胞类型：上皮细胝/span> |
| 形?br/>Morphology |
上皮细胞 |
| 培养基和添加剁br/>Complete Growth Medium and Culture Conditions |
RPMI 1640培养?GIBCO by life technologies ,货号C11875500BT)，添?.01毫克/毫升牛胰岛素?0%；优质胎牛血清，20%、br/>气相：空气，95%；二氧化碳，5%、br/>温度?7摄氏度、/span> |
供应限制
Permits and Restrictions |
A。仅供研究之用、/span> |
| REFERENCE |
Hamilton TC , et al. Characterization of a human ovarian carcinoma cell line (NIH:OVCAR-3) with androgen and estrogen receptors. Cancer Res. 43: 5379-5389, 1983. PubMed: 6604576Hamilton TC , et al. Induction of progesterone receptor with 17beta-estradiol in human ovarian cancer. J. Clin. Endocrinol. Metab. 59: 561-563, 1984. PubMed: 6746867Rogan AM , et al. Reversal of adriamycin resistance by verapamil in human ovarian cancer. Science 224: 994-996, 1984. PubMed: 6372095Hamilton TC , et al. Characterization of a xenograft model of human ovarian carcinoma which produces ascites and intraabdominal carcinomatosis in mice. Cancer Res. 44: 5286-5290, 1984. PubMed: 6333272Green JA , et al. Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion. Cancer Res. 44: 5427-5431, 1984. PubMed: 6488194Caffrey PB , Frenkel GD . Selenite cytotoxicity in drug resistant and nonresistant human ovarian tumor cells. Cancer Res. 52: 4812-4816, 1992. PubMed: 1511444Hamilton TC , et al. Experimental model systems of ovarian cancer: applications to the design and evaluation of new treatment approaches. Semin. Oncol. 11: 285-298, 1984. PubMed: 6385258Godwin AK , et al. High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis. Proc. Natl. Acad. Sci. USA 89: 3070-3074, 1992. PubMed: 1348364Chang K , Pastan I . Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers. Proc. Natl. Acad. Sci. USA 93: 136-140, 1996. PubMed: 8552591Omelyanenko V , et al. HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro. Int. J. Cancer 75: 600-608, 1998. PubMed: 9466663 |
|
|
相关产品
|
