CAS 94367-20-1; n-succinyl-leu-tyr 7-amido-4-*methylcoumarin

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CAS:

94367-20-1

分子式:

C29H33N3O8

分子量:

551.59

英文名称:

n-succinyl-leu-tyr 7-amido-4-*methylcoumarin

用途:

Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

S913166

MACKLIN

Suc-Leu-Tyr-AMC

98%

1800元/50mg;

咨询

储存：-20°C，密闭，干燥

S1153

Sigma-Aldrich

N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin

calpain substrate

1262.35元/5 MG; 2003.96元/10 MG;

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产品说明

包装

5 mg in glass bottle
10 mg in poly bottle

底物

猪钙蛋白酶I和II的底物。

基本信息

经验(实验)分子式	C₂₉H₃₃N₃O₈
分子量	551.59
MDL编号	MFCD00057900
PubChem化学物质编号	24899464
NACRES	NA.32

产品性质

质量水平	200
形式	solid
储存温度	−20℃
SMILES string	CC(C)CC(NC(=O)CCC(O)=O)C(=O)NC(Cc1ccc(O)cc1)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2
InChI	1S/C29H33N3O8/c1-16(2)12-22(31-25(34)10-11-26(35)36)29(39)32-23(14-18-4-7-20(33)8-5-18)28(38)30-19-6-9-21-17(3)13-27(37)40-24(21)15-19/h4-9,13,15-16,22-23,33H,10-12,14H2,1-3H3,(H,30,38)(H,31,34)(H,32,39)(H,35,36)
InChI key	RIYLNECMTVNMSO-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

208731

Sigma-Aldrich

Calpain Substrate II, Fluorogenic-CAS 94367-20-1-Calbiochem

Cyclic fluorogenic substrate for the quantitative determination of calpain -1 and -2.

2966.54元/25 MG;

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产品说明

一般描述

Cyclic fluorogenic substrate for the quantitative determination of calpain -1 and -2. Also suitable for measuring the peptidase activity of the 20S proteasome. Typical concentrations range from 10 - 100 µM, depending on assay conditions.
Fluorogenic substrate for the quantitative determination of porcine calpain I and II activity. Also serves as a substrate for other proteases including proteasome. (excitation wavelength: 380 nm; emission wavelength: 460 nm)

包装

25 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Reversible: no
Primary Target
Calpain -1 and -2
Cell permeable: no

警告

Toxicity: Standard Handling (A)

序列

Suc-Leu-Tyr-AMC

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Seol, J.H., et al. 1989. FEBS Lett. 247, 197.
Woo, K.M., et al. 1989. J. Biol. Chem. 264, 2088.
Sasaki, T., et al. 1984. J. Biol. Chem.259, 12489.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₂₉H₃₁N₃O₇
分子量	533.57
MDL编号	MFCD00057900

产品性质

质量水平	100
测定	≥95% (TLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated protect from light
颜色	off-white
溶解性	DMSO: soluble
荧光	λ_ex ~380 nm λ_em ~460 nm
运输	ambient
储存温度	−20℃
InChI	1S/C29H33N3O8/c1-4-16(2)27(32-24(34)11-12-25(35)36)29(39)31-22(14-18-5-8-20(33)9-6-18)28(38)30-19-7-10-21-17(3)13-26(37)40-23(21)15-19/h5-10,13,15-16,22,27,33H,4,11-12,14H2,1-3H3,(H,30,38)(H,31,39)(H,32,34)(H,35,36)/t16?,22?,27-/m0/s1
InChI key	VSWNAJAOJZXWBM-FTJGSZSVSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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