CAS 923596-52-5; etp-47799 - �뵺�羺�ٷ��ַ

位置：首页 > 资料中心 > 化工字典 > 923596-52-5

CAS:

923596-52-5

分子式:

C₁₄H₁₅N₅

分子量:

253.3

英文名称:

etp-47799

etp 47799

cdk8/19i-cnio-47799

cdk8/19i-47799

n-propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine

lck-in-1

etp47799

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

L937865

MACKLIN

Lck-IN-1

≥98%

978元/5mg; 3944元/25mg;

咨询

储存：2-8°C，密封，干燥
状态：固体

SML3111

Sigma-Aldrich

ETP-47799

≥98% (HPLC)

1222.97元/5 MG; 3943.82元/25 MG;

咨询

产品说明

生化/生理作用

ETP-47799 is a potent and CDK8-/CDK19-selective cyclin-dependent kinase inhibtor (CDK8/19 IC50 = 2.9/14.1 nM; CDK1/5/9 IC50 = 275/239/124 nM; CDK2/4/6/7 IC50 >1 μM; GSK3β IC50 = 3.14 μM) with additional potency against PDGFRα (IC50 = 3.5 nM). ETP-47799 ( 0.4 μM or 1.1 μM) induces and stabilizes the naive state of murine and human pluripotent stem cells (PSCs) with better efficiency than the commonly used MEK/GSK3 inhibitor cocktail (1μM PD0325901, 1.5μM CHIR 99021).

基本信息

经验(实验)分子式	C₁₄H₁₅N₅
分子量	253.30

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	CCCNC1=NN2C(C=C1)=NC=C2C3=CC=NC=C3

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9