| CAS: | 898562-94-2 | |
| 分子式: | C25H20N4O | |
| 分子量: | 392.45 | |
| 英文名称: |
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| 用途: | Mardepodect (PF-2545920) 是一种有效的，口服活性的，选择性的 PDE10A 抑制剂，IC50 为 0.37 nM，比作用于其他 PDE 选择性高 1000 多倍。Mardepodect 可穿过血脑屏障。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||||||
| P910685 | MACKLIN | PF-2545920(MP-10) | 98% | 1268元/5mg; 2348元/10mg; 6290元/50mg; | 咨询 | ||||||||||||||||||||||||||||||||||||
储存：-20°C，密闭，干燥 状态：白色到棕色粉末 | |||||||||||||||||||||||||||||||||||||||||
| PZ0351 | Sigma-Aldrich | PF-2545920 hydrochloride | ≥97% (HPLC) | 1562.86元/5 MG; 6299.25元/25 MG; | 咨询 | ||||||||||||||||||||||||||||||||||||
产品说明 包装 5, 25 mg in glass bottle 生化/生理作用 PF-2545920 hydrochloride (MP-10) is a potent and selective cyclic nucleotide phosphodiesterase (PDE) 10A competitive inhibitor with a reported IC50 value of 1.26 nM. PDE10A hydrolyzes both cAMP and cGMP, and is highly expressed in medium spiny neurons of the mammalian striatum and in basal ganglia areas where D1 and D2 dopamine receptors are expressed. PF-2545920 has been studied for treatment of schizophrenia and Huntington′s disease. 法律信息 Sold for research purposes under agreement from Pfizer Inc. 基本信息
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