CAS 796963-91-2; l-α-lysophosphatidylinositol sodium salt, soy-cas 796963-91-2-calbiochem

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货号

品牌

产品名称

规格

包装、参考价格

440153

Sigma-Aldrich

L-α-lysophosphatidylinositol Sodium Salt, Soy-CAS 796963-91-2-Calbiochem

A potent agonist and assumed endogenous ligand of GPR55.

2005.33元/1 MG;

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产品说明

一般描述

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1 µM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.
A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1uM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

包装

1 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

其他说明

Oka, S., et al. 2010. J Biochem.147, 671.
Oka, S., et al. 2007.
Biochem. Biophys. Res. Commun.362, 928.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₂₅H₄₈NaO₁₂P
分子量	594.61

产品性质

质量水平	100
测定	>99% (HPLC)
形式	powder
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated (hygroscopic) protect from light
颜色	white
溶解性	DMSO: soluble
运输	ambient
储存温度	−20℃
SMILES string	O[C@H]1[C@H](OP(OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O)([O-][Na+])=O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable

850090P

Avanti

Soy Lyso PI

Avanti Polar Lipids 850090P, powder

4213.19元/5 MG; 7053.7元/10 MG;

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产品说明

应用

Soy Lyso PI or L-α-lysophosphatidylinositol (Soy) (sodium salt) has been used:

in giant unilamellar vesicles (GUVs), to measure the effect of LysoPI on membrane bending rigidity
as an exogenous lysophospholipid to study its effect on clathrin-dependent endocytosis
as a substrate to measurement the glycerophosphodiester phosphodiesterases (GP-PDE) and lysophospholipase D activities of the two recombinant mouse GDE4 and GDE7 proteins

生化/生理作用

Lysophosphatidylinositol (LPI) is a bioactive lipid, involved as a signaling mediator in many biological events. It controls cell growth, differentiation and motility. LPI is associated with pathological processes such as cancer cell proliferation.

包装

5 mL Amber Glass Screw Cap Vial (850090P-10mg)
5 mL Amber Glass Screw Cap Vial (850090P-5mg)

基本信息

NACRES

NA.25

产品性质

测定	>99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
形式	powder
包装	pkg of 1 × 10 mg (850090P-10mg) pkg of 1 × 5 mg (850090P-5mg)
manufacturer/tradename	Avanti Polar Lipids 850090P
运输	dry ice
储存温度	−20℃
SMILES string	[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

安全信息

储存分类代码

13 - Non Combustible Solids