CAS 789-61-7; 2-amino-9-(2-deoxy-beta-d-erythro-pentofuranosyl)-9h-purine-6(1h)-thion

CAS:

789-61-7

分子式:

C₁₀H₁₃N₅O₃S

分子量:

283.31

英文名称:

2-amino-9-(2-deoxy-beta-d-erythro-pentofuranosyl)-9h-purine-6(1h)-thion

2'-deoxythioguanosine

beta-2'-deoxythioguanosine

beta-thioguanine deoxyriboside

2'-deoxy-6-thio-guanosin

nci-c01581

tgdr

thioguanine deoxyriboside

用途:

6-thio-dG是一种核苷类似物，也是端粒酶底物。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

T797331

MACKLIN

6-Thio-dG

10mM in DMSO

654元/1ml;

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储存：-20°C

T872534

MACKLIN

6-Thio-dG

99%

488元/5mg; 921元/25mg; 2072元/100mg;

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储存：-20℃
状态：粉末

SML1296

Sigma-Aldrich

6-Thio-2′-Deoxyguanosine

≥97% (HPLC)

1396.09元/5 MG; 4498.97元/25 MG;

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产品说明

应用

6-Thio-2′-Deoxyguanosine has been used in secreted luciferase enzyme activity in tonsillar cancer cells.

包装

5, 25 mg in glass bottle

生化/生理作用

6-Thio-2′-deoxyguanosine (6-thio-dG) is a nucleoside analog and telomerase substrate that is incorporated into de novo–synthesized telomeres. 6-Thio-2′-deoxyguanosine induces telomere dysfunction and rapid cell death in cancer cells, while spearing telomerase-negative cells.

基本信息

经验(实验)分子式	C₁₀H₁₃N₅O₃S
分子量	283.31
PubChem化学物质编号	329825770
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	powder
颜色	white to brown
溶解性	DMSO: 5 mg/mL, clear (warmed)
储存温度	−20℃
SMILES string	S=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)O3)C=N2)N=C(N)N1
InChI	1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5-,6-/m1/s1
InChI key	SCVJRXQHFJXZFZ-HSUXUTPPSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable