CAS 78033-08-6; 8-methoxymethyl-3-isobutyl-1-*methylxanthine

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货号

品牌

产品名称

规格

包装、参考价格

M919030

MACKLIN

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤

≥98%

2160元/5mg; 6860元/25mg;

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储存：2-8°C,密封,干燥

M2547

Sigma-Aldrich

8-Methoxymethyl-3-isobutyl-1-methylxanthine

≥98%

2486.58元/5 MG;

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产品说明

包装

5 mg in glass bottle
25 mg in poly bottle

生化/生理作用

Selective inhibitor of Ca²⁺-calmodulin-dependent phosphodiesterase I (PDE1).

基本信息

经验(实验)分子式	C₁₂H₁₈N₄O₃
分子量	266.30
MDL编号	MFCD00211081
PubChem化学物质编号	24278541
NACRES	NA.77

产品性质

质量水平	200
测定	≥98%
形式	solid
溶解性	ethanol: 10 mg/mL
SMILES string	O=C1C(N=C(COC)N2)=C2N(CC(C)C)C(N1C)=O
InChI	1S/C12H18N4O3/c1-7(2)5-16-10-9(11(17)15(3)12(16)18)13-8(14-10)6-19-4/h7H,5-6H2,1-4H3,(H,13,14)
InChI key	NBLBCGUCPBXKOV-UHFFFAOYSA-N
Gene Information	human ... PDE1A(5136), PDE1B(5153)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

454202

Sigma-Aldrich

8-Methoxymethyl-3-isobutyl-1-methylxanthine-CAS 78033-08-6-Calbiochem

A cell-permeable selective inhibitor of Ca²⁺-calmodulin-dependent phosphodiesterase (PDE I; IC₅₀ = 4 µM).

3945.15元/10 MG;

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产品说明

一般描述

A cell-permeable selective inhibitor of Ca²⁺-calmodulin-dependent phosphodiesterase (PDE I; IC₅₀ = 4 µM).
A cell-permeable, selective inhibitor of Ca²⁺-calmodulin-dependent phosphodiesterase (PDE I, IC₅₀ = 4 µM).

包装

10 mg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Primary Target
PDE 1
Product does not compete with ATP.
Reversible: no
Target IC₅₀: 4 µM against Ca2+-calmodulin-dependent phosphodiesterase (PDE I)

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

其他说明

Jackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
Ahn, H.S., et al. 1989. Biochem. Pharmacol.38, 3331.
Han, P., et al. 1989. J. Biol. Chem.274, 22337.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₁₂H₁₈N₄O₃
分子量	266.30
MDL编号	MFCD00211081

产品性质

质量水平	100
测定	≥98% (TLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze
颜色	white
溶解性	ethanol: 2 mg/mL DMSO: 5 mg/mL
运输	ambient
储存温度	10-30℃
InChI	1S/C12H18N4O3/c1-7(2)5-16-10-9(11(17)15(3)12(16)18)13-8(14-10)6-19-4/h7H,5-6H2,1-4H3,(H,13,14)
InChI key	NBLBCGUCPBXKOV-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

219155

Fluorochem

3-Isobutyl-8-(methoxymethyl)-1-methyl-1H-purine-2,6(3H,7H)-dione

>98%

6424元/10mg; 25564元/50mg;

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基本信息

CAS Number	78033-08-6
MDL Number	MFCD00211081