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CAS: 77-52-1
分子式: C30H48O3
分子量: 456.70
熔点: 283-285℃
中文名称: 
3-羟基-(3β)-乌索12-烯-28-酸
熊果酸
乌苏酸
英文名称: 
Urs-12-en-28-oic acid,3-hydroxy-,(3.beta.)-
3-hydroxy-, (3.beta.)-Urs-12-en-28-oic acid
(3 beta)-urs-12-en-28-oic aci
ursolic acid
3β-Hydroxy-12-ursen-28-ic acid
3beta-Hydroxy-12-ursen-28-oic Acid
推荐供应商
货号品牌产品名称规格包装、参考价格
U820324MACKLIN熊果酸分析对照品, ≥98.5%112元/20mg;   咨询
储存:2~8°C
状态:白色到灰白色粉末,针状和/或块状
U820325MACKLIN熊果酸93%35元/250mg;   72元/1g;   180元/5g;   599元/25g;   2299元/100g;   咨询
储存:2~8°C
状态:白色到灰白色粉末
U820363MACKLIN熊果酸98%58元/250mg;   164元/1g;   560元/5g;   1888元/25g;   5895元/100g;   咨询
储存:2~8°C
状态:白色到灰白色粉末,针状和/或块状
U796882MACKLIN熊果酸10mM in DMSO185元/1ml;   咨询
储存:-20°C
U0065TCIUrsolic Acid>90.0%(GC)540元/100MG;   2190元/1G;   咨询

基本信息

纯度/分析方法>90.0%(GC)
分子式/分子量C30H48O3 = 456.71
外观与形状(20℃)固体
包装和容器 100MG-带有塑料内管的玻璃瓶 (查看图片)
Reaxys-RN2228563
PubChem物质ID87577794
Merck Index (14)9890
MDL编号MFCD00009621

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 90.0 %
Specific rotation [a]20/D+58.0 to +65.0 deg(C=1, Pyridine)

物性(参考值)

比旋光度 [α]D61° (C=1,Pyridine)
583498J&KUrsolic Acid98%306元/25MG;   636元/100MG;   1790元/500MG;   咨询

基本信息

分子式C30H48O3
分子量456.70
熔点292
MDL编码MFCD00009621
Beilstein2228563
EINECS 编号201-034-0
存储条件Store at 2-8℃

安全信息

防范说明P262
WGK3
962881J&KUrsoliicacid来源于山楂叶, 有效含量≥90%, 可溯源至中检院标准品341元/20MG;   咨询

基本信息

分子式C30H48O3
分子量456.7
MDL编码MFCD00009621
C29018Alfa AesarUrsolic Acid95%2526元/250mg;   7415元/1g;   咨询

基本信息

Ref#
29018

MDL
9621

分子式
C30 H48 O3

分子量
456.7

03240595Ursolic Acidprimary reference standard4493.35元/10MG;   咨询

产品说明

一般描述

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

应用

Reference Standard in the analysis of herbal medicinal products

生化/生理作用

三萜类化合物存在于苹果等各类水果中,它是一种心脏保护剂和抗肿瘤剂。由于它能够抑制淀粉样蛋白β和CD36受体之间的相互作用,因此在研究中被用作潜在的阿尔茨海默氏病治疗剂。

基本信息

经验(实验)分子式C30H48O3
分子量456.70
Beilstein2228563
EC 号201-034-0
MDL编号MFCD00009621
PubChem化学物质编号329747577
NACRESNA.24

产品性质

等级primary reference standard
保质期limited shelf life, expiry date on the label
manufacturer/tradenameHWI
mp292 ℃ (dec.) (lit.)
application(s)food and beverages
SMILES string[H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
InChI1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChI keyWCGUUGGRBIKTOS-GPOJBZKASA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)580.5 °F
闪点(C)304.7 ℃
Y0001523Ursolic AcidEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

三萜类化合物存在于苹果等各类水果中,它是一种心脏保护剂和抗肿瘤剂。由于它能够抑制淀粉样蛋白β和CD36受体之间的相互作用,因此在研究中被用作潜在的阿尔茨海默氏病治疗剂。

包装

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C30H48O3
分子量456.70
Beilstein2228563
MDL编号MFCD00009621
PubChem化学物质编号329831473
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp292 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES string[H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
InChI1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChI keyWCGUUGGRBIKTOS-GPOJBZKASA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)580.5 °F
闪点(C)304.7 ℃
89797SupelcoUrsolic Acidanalytical standard1687.64元/5 MG;   6687.78元/25 MG;   咨询

产品说明

一般描述

熊果酸属于三萜类化合物,广泛存在于草药、食品和其他植物中。它可能具有药理活性,如心脏保护、镇痛、强心、镇静和滋补作用。

应用

有关合适仪器技术的更多信息,请参考产品′s分析证书。如需进一步支持,请联系技术服务。

生化/生理作用

三萜类化合物存在于苹果等各类水果中,它是一种心脏保护剂和抗肿瘤剂。由于它能够抑制淀粉样蛋白β和CD36受体之间的相互作用,因此在研究中被用作潜在的阿尔茨海默氏病治疗剂。

基本信息

经验(实验)分子式C30H48O3
分子量456.70
Beilstein2228563
EC 号201-034-0
MDL编号MFCD00009621
PubChem化学物质编号329769543
NACRESNA.24

产品性质

等级analytical standard
质量水平100
测定≥98.5% (HPLC)
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp292 ℃ (dec.) (lit.)
application(s)food and beverages
格式neat
SMILES string[H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
InChI1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChI keyWCGUUGGRBIKTOS-GPOJBZKASA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)580.5 °F
闪点(C)304.7 ℃
个人防护装备Eyeshields, Gloves, type N95 (US)
U6753Sigma-AldrichUrsolic Acid≥90%758.68元/100 MG;   2969.5元/500 MG;   咨询

产品说明

一般描述

熊果酸(UA)是一种羟基五环三萜酸(HPTA),具有抗菌、 抗癌、 抗氧化和抗炎作用。它还可以促进周围神经损伤后的神经再生。UA可以激活GABA能神经递质系统,从而延长睡眠持续时间。[GABA= γ-氨基丁酸]

应用

熊果酸可作为起始材料,用于与氯乙酸乙酯反应合成熊果酸乙氧甲酰基甲酯(ECU)。ECU可作为关键中间体,用于全合成重要的生物化合物3-乙酰基-2-[(未)取代苯基]-2,3-二氢-1,3,4-噁二唑-5-甲酯 3-O-乙酰基熊果酸。熊果酸也可用于制备新型杂环衍生物,以便进行各种活性研究。

包装

500 mg in poly tube
100 mg in poly bottle

生化/生理作用

三萜类化合物存在于苹果等各类水果中,它是一种心脏保护剂和抗肿瘤剂。由于它能够抑制淀粉样蛋白β和CD36受体之间的相互作用,因此在研究中被用作潜在的阿尔茨海默氏病治疗剂。

其他说明

Scripps Center for Metabolomics(斯克里普斯代谢组学中心)独立生成的串联质谱数据,可以PDF格式查看或下载。 U6753.pdf 经过测试的代谢物在Scripps Center for Metabolomics(斯克里普斯代谢组学中心) METLIN 代谢物数据库中有重点介绍。更多信息请见sigma.com/metlin。

基本信息

经验(实验)分子式C30H48O3
分子量456.70
Beilstein2228563
EC 号201-034-0
MDL编号MFCD00009621
PubChem化学物质编号57654721
NACRESNA.22

产品性质

质量水平100
测定≥90%
mp292 ℃ (dec.) (lit.)
储存温度2-8℃
SMILES string[H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
InChI1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChI keyWCGUUGGRBIKTOS-GPOJBZKASA-N
Gene Informationmouse ... Ifng(15978), Nos2(18126)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)580.5 °F
闪点(C)304.7 ℃
个人防护装备Eyeshields, Gloves, type N95 (US)
PHL89541Ursolic Acidphyproof® Reference Substance3312.99元/25 MG;   咨询

产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

生化/生理作用

三萜类化合物存在于苹果等各类水果中,它是一种心脏保护剂和抗肿瘤剂。由于它能够抑制淀粉样蛋白β和CD36受体之间的相互作用,因此在研究中被用作潜在的阿尔茨海默氏病治疗剂。

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式C30H48O3
分子量456.70
Beilstein2228563
MDL编号MFCD00009621

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥95.0% (HPLC)
形式powder
manufacturer/tradenamePhytoLab
mp292 ℃ (dec.) (lit.)
SMILES string[H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
InChI1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChI keyWCGUUGGRBIKTOS-GPOJBZKASA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)580.5 °F
闪点(C)304.7 ℃
1707770USPUrsolic AcidUnited States Pharmacopeia (USP) Reference Standard2829.07元/25 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

三萜类化合物存在于苹果等各类水果中,它是一种心脏保护剂和抗肿瘤剂。由于它能够抑制淀粉样蛋白β和CD36受体之间的相互作用,因此在研究中被用作潜在的阿尔茨海默氏病治疗剂。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C30H48O3
分子量456.70
Beilstein2228563
MDL编号MFCD00009621
PubChem化学物质编号329751467
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp292 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度15-25℃
SMILES string[H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
InChI1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChI keyWCGUUGGRBIKTOS-GPOJBZKASA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)580.5 °F
闪点(C)304.7 ℃
672315Sigma-AldrichUrsolic Acid-CAS 77-52-1-CalbiochemA cell-permeable plant-derived pentacyclic triterpene acid that displays anti-inflammatory, immunomodulatory, and antitumor activities.1164.01元/50 MG;   咨询

产品说明

一般描述

A cell-permeable plant-derived pentacyclic triterpene acid that displays anti-inflammatory, immunomodulatory, and antitumor activities. Shown to inhibit the phosphatase activity of SHP2, PTP1B, and TCPTP (IC50 = 2.73, 3.08 and 3.33 µM, respectively) as well as induce IR autophosphorylation independent of its phosphatase inhibitory activity. Ursolic acid is also reported to inhibit NF-κB and STAT3 pathway activation in cancer cultures, resulting in enhanced sensitivity to chemotherapy agents and apoptotic cell death.

包装

50 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Li, Y., et al. 2010. Int. J. Cancer127, 462.
Pathak, A.K., et al. 2007. Mol. Cancer Res.5, 943.
Jung, S.H., et al. 2007. Biochem. J.403, 243.
Zhang, W., et al. 2006. Biochim. Biophys. Acta1760, 1505.
Shishodia, S., et al. 2003. Cancer Res.63, 4375.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C30H48O3
分子量456.70
MDL编号MFCD00009621

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white
溶解性ethanol: 3.5 mg/mL
DMSO: 50 mg/mL
运输ambient
储存温度2-8℃
InChI1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChI keyWCGUUGGRBIKTOS-GPOJBZKASA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)580.5 °F
闪点(C)304.7 ℃
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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