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CAS: 77-22-5
分子式: C18H27NO2
分子量: 289.42
中文名称: 
1-苯基环戊烷羧酸-β-二乙氨基乙酯
咳美芬盐基
英文名称: 
1-Phenylcyclopentanecarboxylic acid -diethylaminoethyl ester
1-phenyl-cyclopentanecarboxylic aci 2-(diethylamino)ethyl ester
1-phenylcyclopentanecarboxylic acid 2-(diethylamino)ethyl ester
parpanil
pentaphen (pharmaceutical)
性质描述: 液体。沸点156-158℃(0.93kPa),110-115℃(6.65×10-3kPa)。
生产方法: 由1-苯基环戊烷甲酰氯与二乙氨基乙醇经酯化而得。将1-苯基环戊烷甲酰氯加入干燥的反应锅内,搅拌冷至10-15℃,滴加二乙氨基乙醇,内温逐渐上升至110℃,于2.5-3h内加毕,搅拌30min,升温至115-125℃,反应2-2.5h,趁热放料,放置过夜。加5倍量的水溶解,加10%盐酸至pH=6-7。过滤除去不溶物。滤液用苯提取后,加活性炭,于70-80℃脱色2h,过滤。滤液加碳酸钠至中性,析出油层,用硫酸钠饱和溶液洗至中性,再加无水硫酸钠干燥,过滤,得咳美芬盐基。
用途: 该品与乙烷二磺酸成盐,即为止咳药咳美芬,有抑制咳嗽中枢的作用。用于肺结核、气管炎、支气管炎、流感引起的咳嗽。
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货号品牌产品名称规格包装、参考价格
Y0000099Pentoxyverine impurity BEuropean Pharmacopoeia (EP) Reference Standard1295.6元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C18H27NO2
分子量289.41
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/C18H27NO2/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3
InChI keyOFAIGZWCDGNZGT-UHFFFAOYSA-N
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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