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CAS: 76963-41-2
分子式: C12H21N5O2S2
分子量: 331.45
中文名称: 
尼扎替丁
英文名称: 
1,1-ethenediamine, n-(2-(((2-((dimethylamino)methyl)-4-thiazolyl)methyl)thio)et
hyl)-n'- methyl-2-nitro-
1,1-ethenediamine, n-[2-[[[2-[(dimethylamino)methyl]-4-thiazoly]methyl]thio]- e
thyl]-n'-methyl-2-nitro-
axid
calmaxid
cronizat
gastrax
ly 139037
n-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]-n'-methyl-2-nitro-1,
1-ethenediamine
naxidine
nizatidine
nizax
nizaxid
zanizal
ze-101
zl-101
展开更多英文名
用途: 用于活动性十二指肠溃疡和良性溃疡药。
推荐供应商
货号品牌产品名称规格包装、参考价格
N795367MACKLIN尼扎替丁10mM in DMSO463元/1ml;   咨询
储存:-20°C
N0933TCINizatidine>97.0%(T)(HPLC)395元/5G;   1590元/25G;   咨询

基本信息

纯度/分析方法>97.0%(T)(HPLC)
分子式/分子量C12H21N5O2S2 = 331.45
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气
Reaxys-RN4846056
PubChem物质ID253661718
Merck Index (14)6660
MDL编号MFCD00865660

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(HPLC)min. 97.0 area%
Purity(Nonaqueous Titration)min. 97.0 %
Melting point130.0 to 134.0 ℃

物性(参考值)

熔点132 ℃
水溶性微溶
溶解性(易溶于)二甲基甲酰胺
溶解性(可溶于)甲醇,二氯甲烷
溶解度(极微溶)乙醇,丙酮
溶解性(不溶于)乙醚

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#KM6565000
429548J&KNizatidine99%436元/5G;   1511元/25G;   4976元/100G;   咨询

基本信息

分子式C12H21N5O2S2
分子量331.46
熔点130-134
MDL编码MFCD00865660
Beilstein4846056
Merck14, 6660

安全信息

图形或危害标志
危险说明H302
防范说明P264
P270
P301+P312+P330
P501
RTECSKM6565000
C46847Alfa AesarNizatidine2635元/5g;   7063元/25g;   咨询

基本信息

分子式
C12 H21 N5 O2 S2

分子量
331.45

N1090000NizatidineEuropean Pharmacopoeia (EP) Reference Standard1286.46元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 250 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C12H21N5O2S2
分子量331.46
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3/b11-6+
InChI keySGXXNSQHWDMGGP-IZZDOVSWSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
Y0001278Nizatidine for system suitabilityEuropean Pharmacopoeia (EP) Reference Standard1176.99元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C12H21N5O2S2
分子量331.46
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3/b11-6+
InChI keySGXXNSQHWDMGGP-IZZDOVSWSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
N7035SupelcoNizatidineanalytical standard591.92元/5 G;   咨询

产品说明

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Histamine H2 receptor antagonist. Used to treat gastroesophogeal reflux disease by preventing release of acid and pepsin into the stomach.

包装

5, 10 g in glass bottle

基本信息

经验(实验)分子式C12H21N5O2S2
分子量331.46
MDL编号MFCD00865660
PubChem化学物质编号329818669
NACRESNA.24

产品性质

等级analytical standard
质量水平100
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCN\C(NCCSCc1csc(CN(C)C)n1)=C/[N+]([O-])=O
InChI1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3/b11-6+
InChI keySGXXNSQHWDMGGP-IZZDOVSWSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
SML2960Sigma-AldrichNizatidine≥98% (HPLC)416.36元/500 MG;   咨询

产品说明

生化/生理作用

Nizatidine is a potent and selective antagonist of histamine H2 receptors used for treatment of stomach and intestine ulcers. Also, it was recommended as a component of combination therapy for cancer treatment. New data indicate that it can be repurposed to treat subtypes of clear cell renal cell carcinoma (ccRCC) in patients expressing certain isoforms of the pyruvate kinase muscle type. Additionally, nizatidine increases utrophin A levels in in C2C12 myoblasts (relevant to Duchenne muscular dystrophy).

基本信息

经验(实验)分子式C12H21N5O2S2
分子量331.46

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃
InChI1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3/b11-6+
InChI keySGXXNSQHWDMGGP-IZZDOVSWSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1467804USPNizatidineUnited States Pharmacopeia (USP) Reference Standard7060.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C12H21N5O2S2
分子量331.46
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
InChI1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3/b11-6+
InChI keySGXXNSQHWDMGGP-IZZDOVSWSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
358089Fluorochem[1-({2-[({2-[(dimethylamino)methyl]-1,3-thiazol-4-yl}methyl)sulfanyl]ethyl}amino)-2-nitroethenyl](methyl)amine>97.0%(HPLC)(T)968元/5g;   3190元/25g;   咨询

基本信息

CAS Number76963-41-2
MDL NumberMFCD00865660
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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