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CAS: 765317-72-4
分子式: C26H19Br2N3O7S3
分子量: 504.14
中文名称: 
ptp1b 抑制剂
英文名称: 
ptp1b inhibitor
3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-n-[4-(2-thiazolylsulfamoyl)phenyl]benzofuran-6-sulfonamide
推荐供应商
货号品牌产品名称规格包装、参考价格
P970559MACKLINPTP1B抑制剂95%332元/1mg;   844元/5mg;   咨询
储存:-20°C, 避光
539741Sigma-AldrichPTP1B Inhibitor-CAS 765317-72-4-CalbiochemPTP1B Inhibitor, CAS 765317-72-4, is a cell-permeable, selective, reversible and non-competitive allosteric inhibitor of PTP1B (IC₅₀ = 4 µM and 8 µM for PTP1B403 and PTP1B298, re3736.22元/5 MG;   咨询

产品说明

一般描述

A cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC50 = 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop. Also available in InSolution format (Cat. No. 539749.

包装

5 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Target IC50: 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively
Product does not compete with ATP.
Primary Target
PTP1B403
Reversible: yes

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Wiesmann, C., et al. 2004. Nat. Struct. Mol. Biol.11, 730.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C26H19Br2N3O7S3
分子量741.45

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white
溶解性DMSO: 100 mg/mL
ethanol: 5 mg/mL
运输wet ice
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
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