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CAS: 76-83-5
分子式: C19H15Cl
分子量: 278.78
沸点: 230-235℃
熔点: 108-114℃
中文名称: 
三苯基氯甲烷
英文名称: 
chlorotriphenyl-methan
1,1',1''-(chloromethylidyne)tris-benzen
chlorotriphenylmethane
triphenylchloromethane
triphenylmethyl chloride
trityl chloride
Triphenyl chloeomethane
Benzene,(chlorodiphenylmethyl)-
1,1',1''(-Chloromethylidyne)trisben-zene
性质描述: 熔点111-112℃,沸点230-235℃。
生产方法: 干燥无噻吩的苯与四氯化碳混合冷至0-5℃,加入三氯化铝,搅拌反应中放出大量氯化氢气体。将反应物加入预冷的苯和盐酸的混合物中,在25℃以下水解。反应完毕,分取苯层。加热蒸去苯,冷至40℃、加乙酰氯少许,加热回流片刻。冷却,滤除母液,滤饼用石油醚、苯各洗一次,干燥,即得三苯氯甲烷。
用途: 用于合成抗病毒药碘甙。
推荐供应商
货号品牌产品名称规格包装、参考价格
T819044MACKLIN三苯基氯甲烷97%29元/25g;   42元/100g;   107元/500g;   492元/2.5kg;   咨询
储存:室温,存于惰性气体中
状态:白色到灰白色到棕褐色粉末或晶体
C0308TCITrityl Chloride>98.0%(T)195元/25G;   330元/100G;   680元/500G;   咨询

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C19H15Cl = 278.78
外观与形状(20℃)固体
储存温度0-10℃
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (分解),加热
Reaxys-RN397363
PubChem物质ID87565459
SDBS (AIST Spectral DB)7456
MDL编号MFCD00000813

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(Argentometric Titration)min. 98.0 %
Melting point110.0 to 115.0 ℃

物性(参考值)

熔点113 ℃
沸点310 ℃
溶解性(易溶于)乙醚,苯,氯仿
溶解性(可溶于)丙酮
溶解性(微溶于)

安全信息

图形或危害标志
信号词危险
危险性说明H314 : 造成严重皮肤灼伤和眼损伤。
H290 : 可能腐蚀金属。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P260 : 不要吸入粉尘或烟雾。
P234 : 只能在原容器中存放。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P390 : 吸收溢出物,防止材料损坏。
P303 + P361 + P353 : 如皮肤(或头发)沾染:立即脱掉所有沾污的衣物。用水清洗皮肤/淋浴。
P301 + P330 + P331 : 如误吞咽:漱口。不要诱导呕吐。
P363 : 沾染的衣服清洗后方可重新使用。
P304 + P340 + P310 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。立即呼叫急救中心/医生。
P305 + P351 + P338 + P310 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。
P406 : 贮存于抗腐蚀/带抗腐蚀衬里的容器中。
P405 : 存放处须加锁。

相关法规

RTECS#PA6450000

运输信息

UN编号UN3261
类别8
包装类别 III
监管条件代码(*)
171149J&KTrityl Chloride99%60元/25G;   139元/100G;   493元/500G;   咨询

基本信息

分子式C19H15Cl
分子量278.78
熔点109-112
沸点230-235
MDL编码MFCD00000813
Beilstein397363
EINECS 编号200-986-4

安全信息

图形或危害标志
提示语Danger
危险说明H314
防范说明P280
P305+P351+P338
P310
UN号码3261
危险分类8
包装等级III
WGK3
RTECSPA6450000
TSCA
A11799Alfa AesarChlorotriphenylmethane98%221元/25g;   348元/100g;   1417元/500g;   咨询

应用
Chlorotriphenylmethane is used as laboratory chemical. It acts as a protecting reagent for thiols, alcohols and amines. It is used in organic synthesis for initiating trityl group protection and for preparing S-trityl-L-cysteine (STLC), a inhibitor of Eg5 prevents mitotic progression.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00000813

EINECS
200-986-4

分子式
C19H15Cl

分子量
278.78

熔点
110-114°

沸点
230-235°/20mm

灵敏度
Moisture Sensitive. Ambient temperatures.

形态
Crystalline powder

溶解性
Insoluble in water. Soluble in chloroform, hexane, benzene, ether, acetone and tetrahydrofuran.

Beilstein
397363

GHS危害和防范说明

GHS符号

Hazard Statements
H314-H318-H400-H410
Causes severe skin burns and eye damage.Causes serious eye damage.Very toxic to aquatic life.Very toxic to aquatic life with long lasting effects.

Precautionary Statements
P273-P280-P305+P351+P338-P309-P310
Avoid release to the environment.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.

安全信息

危险等级
8

包装组
II

危险类别
34-50/53
Causes burns.Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

安全等级
26-36/37/39-45-60-61
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous wasteAvoid release to the environment. Refer to special instructions/safety data sheets.

欧盟危险品标志

RTECS
PA6450000

TSCA

C14040Alfa AesarTriphenylmethyl Chloride98%651元/100g;   2590元/500g;   8368元/2.5kg;   咨询

基本信息

Ref#
14040

MDL
813

分子式
C19 H15 Cl

分子量
278.77

安全信息

危险等级
8

包装组
III

T83801Sigma-AldrichTrityl Chloride97%202.91元/25 G;   530.4元/100 G;   2041.4元/500 G;   咨询

产品说明

应用

胺、醇和硫醇的保护剂。
三苯甲基氯可用作以下应有的催化剂:

  • Ritter型合成,通过萘酚,芳基醛和乙腈进行一锅三组分反应,合成1-氨基烷基-2-萘酚。
  • 通过偶苯酰与醛、伯胺以及乙酸铵进行一锅多组分反应,合成1,2,4,5-四取代咪唑。
  • 在无溶剂条件下通过酚、芳香醛和酰胺进行一锅多组分反应制备酰胺烷基酚。
  • 通过芳香醛、胺和β-酮酯进行一锅多组分反应合成取代哌啶。

包装

25, 100, 500 g in poly bottle

基本信息

线性分子式(C6H5)3CCl
分子量278.78
Beilstein397363
EC 号200-986-4
MDL编号MFCD00000813
PubChem化学物质编号24900525

产品性质

质量水平200
测定97%
bp230-235 ℃/20 mmHg (lit.)
mp109-112 ℃ (lit.)
SMILES stringClC(c1ccccc1)(c2ccccc2)c3ccccc3
InChI1S/C19H15Cl/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
InChI keyJBWKIWSBJXDJDT-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H314
预防措施声明P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
危险分类Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
8.08348Sigma-AldrichChlorotriphenylmethanefor synthesis701.48元/250 G;   913.11元/1 KG;   咨询

基本信息

线性分子式ClC(C6H5)3
分子量278.78
MDL编号MFCD00000813
EC索引号200-986-4

产品性质

质量水平200
效能>5000 mg/kg LD50, oral (Rat)
bp230-235 ℃/27 hPa
mp109-112 ℃
储存温度2-30℃
InChI1S/C19H15Cl/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
InChI keyJBWKIWSBJXDJDT-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H314
预防措施声明P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
危险分类Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
93000Sigma-AldrichTrityl Chloridepurum, ≥97.0% (HPLC), ≥97.0% (AT)277.93元/100 G;   1320.19元/500 G;   8973.3元/5 KG;   咨询

产品说明

包装

100, 500 g in glass bottle
5 kg in poly drum

其他说明

用于三苯甲基化的试剂;对敏感化合物进行三苯甲基化和随后的去三苯甲基化的有效方法

基本信息

线性分子式(C6H5)3CCl
分子量278.78
Beilstein397363
EC 号200-986-4
MDL编号MFCD00000813
PubChem化学物质编号329770191
NACRESNA.22

产品性质

质量水平200
等级purum
测定≥97.0% (AT)
≥97.0% (HPLC)
灼烧残渣≤0.2% (as SO4)
bp230-235 ℃/20 mmHg (lit.)
mp109-112 ℃ (lit.)
109-113 ℃
溶解性chloroform: 0.1 g/mL, clear
SMILES stringClC(c1ccccc1)(c2ccccc2)c3ccccc3
InChI1S/C19H15Cl/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
InChI keyJBWKIWSBJXDJDT-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H314
预防措施声明P280 - P305 + P351 + P338 - P310
危险分类Skin Corr. 1B
储存分类代码8B - Non-combustible, corrosive hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
129062AmethystTrityl Chloride99%, 用于合成42元/25G;   79元/100G;   207元/500G;   828元/2.5KG;   咨询

基本信息

分子式C19H15Cl
分子量278.78
熔点109-112
沸点230-235
MDL编码MFCD00000813
Beilstein397363
EINECS 编号200-986-4

安全信息

图形或危害标志
提示语Danger
危险说明H314
防范说明P280
P305+P351+P338
P310
UN号码3261
危险分类8
包装等级III
WGK3
RTECSPA6450000
TSCA
M02871FluorochemTrityl Chloride>98%220元/25g;   220元/100g;   616元/250g;   748元/500g;   咨询

基本信息

CAS Number76-83-5
MDL NumberMFCD00000813
Melting Point109- 116℃

安全信息

图形或危害标志
危险性说明 H314: Causes severe skin burns and eye damage.
H335: May cause respiratory irritation.
H410: Very toxic to aquatic life with long lasting effects.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear .
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P363: Wash contaminated clothing before reuse.
P391: Collect spillage.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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