CAS 74389-68-7; 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

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货号

品牌

产品名称

规格

包装、参考价格

O937871

MACKLIN

1-O-十六烷基-2-乙酰基-sn-甘油-3-磷酸胆碱

≥98%

1382元/5mg; 5000元/25mg;

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储存：-20°C，密封，干燥
状态：无色晶体

155439

J&K

β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine

98%

4818元/25MG;

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基本信息

分子式	C₂₆H₅₄NO₇P
分子量	523.68
MDL编码	MFCD00043214
Beilstein	3574588
存储条件	Freezer -20℃

生化/生理作用

细胞外信号脂质；G蛋白偶联血小板活化因子（PAF）受体的配体。通过增加血管通透性诱导炎症；激活CHO细胞中的MAP激酶（MAPK）和MAP激酶激酶（MAPKK）。

安全信息

防范说明	P262
WGK	3

511075

Sigma-Aldrich

Platelet Activating Factor-16-CAS 74389-68-7-Calbiochem

A potent mediator of inflammation that increases vascular permeability. Activates MAP kinases and MAP kinase kinase (MEK) in CHO cells.

715.88元/1 MG; 1633.58元/5 MG;

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产品说明

一般描述

Synthetic. A potent mediator of inflammation that increases vascular permeability. Activates MAP kinases and MAP kinase kinase (MEK) in CHO cells.
Synthetic water-soluble platelet activating factor. A potent mediator of inflammation that increases vascular permeability. Activates MAP kinase and MAP kinase kinase (MEK) in CHO cells.

包装

5 mg in Glass bottle
1 mg in Plastic ampoule

生化/生理作用

Primary Target
MAP kinases and MAP kinase kinase (MEK)
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C or -70°C) under an inert gas. Aqueous stock solutions are stable for up to 3 days at -20°C. Ethanol stock solutions are stable for up to 3 months at -70°C.

其他说明

Honda, Z., et al. 1994. J. Biol. Chem. 269, 2307.
Mori, M., et al. 1994. Ann. N.Y. Acad. Sci.744, 107.
Pinckard, R.N., et al. 1992. J. Immunol.148, 3528.
Salari, H., et al. 1992. Biochem. Cell Biol.70, 129.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₂₆H₅₄NO₇P
分子量	523.68

产品性质

质量水平	100
测定	≥98% (TLC)
形式	lyophilized solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated
颜色	white to off-white
溶解性	ethanol: 0.5-1 mg/mL water: soluble
运输	ambient
储存温度	−20℃
InChI	1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1
InChI key	HVAUUPRFYPCOCA-AREMUKBSSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

P4904

Sigma-Aldrich

β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate

≥98%

686.1元/1 MG; 1682.59元/5 MG; 3215.2元/10 MG; 7891.47元/25 MG;

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产品说明

生化/生理作用

细胞外信号脂质；G蛋白偶联血小板活化因子(PAF)受体的配体。通过增加血管通透性诱导炎症；激活CHO细胞中的MAP激酶(MAPK)和MAP激酶激酶(MAPKK)。

基本信息

经验(实验)分子式	C₂₆H₅₄NO₇P · xH₂O
分子量	523.68 (anhydrous basis)
Beilstein	3574588
MDL编号	MFCD00150679
PubChem化学物质编号	24898570
NACRES	NA.77

产品性质

质量水平	200
测定	≥98%
储存温度	−20℃
SMILES string	O.CCCCCCCCCCCCCCCCOC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(C)=O
InChI	1S/C26H54NO7P.H2O/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5;/h26H,6-24H2,1-5H3;1H2/t26-;/m1./s1
InChI key	HFMSDOHEENWULV-UFTMZEDQSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

878110P

Avanti

C16-02:0 PC

Avanti Polar Lipids 878110P, powder

1527.91元/5 MG; 5341.24元/25 MG;

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产品说明

一般描述

C16-02:0 PC, also referred as 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16 PAF) (acetyl PAF), is a platelet-activating factor (PAF). Acetyl PAF is a natural PAF with ether-linked hexadecyl chain at the sn-1 position and an acetyl group at the sn-2 position.

应用

C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. It may also be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.

生化/生理作用

C16-02:0 PC, a platelet-activating factor and a lipid mediator is involved in various inflammatory diseases. It facilitates initiation and progression of atherosclerosis. PAF acts as a potential biomarker for coronary artery diseases. It exhibits its activity by binding to a specific PAF receptor, which belongs to the seven transmembrane-spanning G-protein-linked receptors family. PAF on hydrolysis by platelet-activating factor-acetyl hydrolase produces LysoPAF (1-O-alkyl-2-hydroxy-sn-glycero-3-phosphocholine).

包装

5 mL Clear Glass Sealed Ampule (878110P-25mg)
5 mL Clear Glass Sealed Ampule (878110P-5mg)

基本信息

经验(实验)分子式	C₂₆H₅₄NO₇P
分子量	523.68
NACRES	NA.25

产品性质

形式	powder
包装	pkg of 1 × 25 mg (878110P-25mg) pkg of 1 × 5 mg (878110P-5mg)
manufacturer/tradename	Avanti Polar Lipids 878110P
运输	dry ice
储存温度	−20℃
SMILES string	[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCC)=O
InChI	1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1
InChI key	HVAUUPRFYPCOCA-AREMUKBSSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable