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CAS: 7414-83-7
分子式: C2H8O7P2·2Na
分子量: 249.99
熔点: >300 °C
中文名称: 
依替膦酸二钠
(1-羟亚乙基)-二膦酸二钠
英文名称: 
ethane-1-hydroxy-1,1-diphosphonic acid, disodium salt
etidronate disodium
(1-hydroxyethane-1,1-diyl)di-phosphonic aci disodium salt
(1-hydroxyethylidene)bis-phosphonic aci disodium salt
sm-5600
sodium ethidronate
sodium ethydronate
sodium etidronate
sodiumetidronate
Phosphonic acid,(1-hydroxyethylidene)bis-,disodium salt
Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt
(1-hydroxyethylidene)di-phosphonic aci disodium salt
(1-hydroxyethane-1,1-diyl)diphosphonic acid disodium salt
(1-hydroxyethylidene)diphosphonic acid, disodium salt
1-hydroxyethylidene-1,1-diphosphonic acid disodium salt
didronel r
disodium (1-hydroxyethylidene)diphosphonate
disodium 1-hydroxyethylidene phosphonate
disodium dihydrogen (1-hydroxyethylidene)diphosphonate
disodium ethanol-1,1-diphosphonate
disodium ethydronate
disodium etidronate
展开更多英文名
用途: 骨吸收抑制剂,用于原发性骨质疏松和绝经后骨质疏松症。
推荐供应商
货号品牌产品名称规格包装、参考价格
D832340MACKLIN羟乙膦酸钠98%36元/1g;   61元/5g;   165元/25g;   399元/100g;   1898元/500g;   9054元/2.5kg;   咨询
储存:2~8℃,Dry
状态:白色晶体粉末
D794225MACKLINDisodium etidronate10mM in Water720元/1ml;   咨询
储存:-20°C
D4159TCIDisodium Etidronate Hydrate>98.0%(T)915元/5G;   3085元/25G;   咨询

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C2H6Na2O7P2・xH2O = 249.99
外观与形状(20℃)固体
储存温度0-10℃
应避免的情况加热
Reaxys-RN5190835
PubChem物质ID160871185
Merck Index (14)3863
MDL编号MFCD00152567

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Ion exchange titration)min. 98.0 %(after drying)
Drying lossmax. 5.0 %

物性(参考值)

水溶性可溶

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#SZ8562240
237817J&KEtidronate disodium hydrate98%, 蛋白质酪氨酸磷酸酶抑制剂817元/5G;   2651元/25G;   咨询

基本信息

分子式C2H6Na2O7P2·xH2O
分子量249.99(anhydrous)
熔点>300
MDL编码MFCD00152567
Beilstein5190835
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H302
防范说明P280
WGK1
RTECSSZ8562240
J62381Alfa AesarEtidronate disodium4288元/1g;   咨询

应用
Etidronate disodium is used as a bisphosphonate bone resorption inhibitor. Etidronic acid is used as a calcium regulator. Etidronic acid is a bisphosphonate antiresorptive agent.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8?°C. Keep away from strong oxidizing agents.

基本信息

MDL
MFCD00152567

EINECS
231-025-7

分子式
C2H6Na2O7P2

分子量
249.99

熔点
>300°

灵敏度
Keep Cold.

形态
Crystalline solid

溶解性
Soluble in water (26 mg/ml).

Merck
14,3863

GHS危害和防范说明

GHS符号

Hazard Statements
H302
Harmful if swallowed.

Precautionary Statements
P264-P270-P301+P312a-P330-P501a
Wash thoroughly after handling.Do not eat, drink or smoke when using this product.Do not eat, drink or smoke when using this product.Rinse mouth.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
22
Harmful if swallowed.

安全等级
36-60
Wear suitable protective clothing.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

TSCA

Y0000572Etidronate disodiumEuropean Pharmacopoeia (EP) Reference Standard1259.15元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C2H6Na2O7P2
分子量249.99
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2
InChI keyGWBBVOVXJZATQQ-UHFFFAOYSA-L

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
P5248Sigma-AldrichEtidronate disodium hydrate≥97% (NMR), solid1156.54元/10 MG;   7276.99元/100 MG;   咨询

产品说明

应用

Etidronate disodium hydrate has been used in the synthesis of bisphosphonate derivatives of adenosine triphosphate (ATP)by T4 RNA ligase. It has also been sued to inhibit human farnesyl diphosphate synthase (FDPS).

包装

10, 100 mg in glass bottle

生化/生理作用

Etidronate helps to guard chronic ocular hypertension prompted retinal oxidative stress. It stimulates the development of retinal ganglion cells through insulin-like growth factor 1 (IGF-1) signaling pathway. It may possess neuroprotective effects in in vivo and in vitro rat model of glaucoma. Etidronate belongs to bisphosphonates.
Bisphosphonate antiresorptive agent. Less potent inhibitor of farnesyl diphosphate synthase (IC50 = 80 μM) as compared to the nitrogen containing bisphosphonates

基本信息

经验(实验)分子式C2H6Na2O7P2 · xH2O
分子量249.99 (anhydrous basis)
EC 号231-025-7
MDL编号MFCD00152567
PubChem化学物质编号329820220
NACRESNA.77

产品性质

质量水平100
测定≥97% (NMR)
形式solid
颜色 white
mp>300 ℃
溶解性H2O: ≥10 mg/mL
储存温度2-8℃
SMILES string[Na+].[Na+].CC(O)(P(O)([O-])=O)P(O)([O-])=O
InChI1S/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2
InChI keyGWBBVOVXJZATQQ-UHFFFAOYSA-L

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
1268502USPEtidronate disodiumUnited States Pharmacopeia (USP) Reference Standard3036.37元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C2H6Na2O7P2
分子量249.99
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度15-25℃
InChI1S/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2
InChI keyGWBBVOVXJZATQQ-UHFFFAOYSA-L

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
097820Fluorochem(1-Hydroxyethylidene)bis-phosphonic acid disodium salt>98.0%(T)1562元/5g;   5390元/25g;   咨询

基本信息

CAS Number7414-83-7
MDL NumberMFCD00152567
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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