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CAS: 7380-40-7
分子式: C21H22O4
分子量: 338.4
英文名称: 
bergamottin
Bergamotine
用途: Bergamottin 是一种有效的竞争性 CYP1A1 抑制剂,Ki 为 10.703 nM。
推荐供应商
货号品牌产品名称规格包装、参考价格
B877584MACKLINBergamottin99%199元/1mg;   693元/5mg;   1048元/10mg;   1989元/25mg;   咨询
储存:2-8℃
状态:白色到灰白色固体
929336J&KBergamottin98%, 来源于佛手1250元/20MG;   咨询

基本信息

分子式C21H22O4
分子量338.4
MDL编码MFCD00017409
01338SupelcoBergamottinanalytical standard2507.92元/5MG-F;   咨询

产品说明

一般描述

Bergamottin, a member of the furanocoumarin family, is primarily found in grapefruit juice. It is reported to be a novel signal transducer and activator of the transcription 3 (STAT3) inhibitor. It is a known drug inhibitor of cytochrome P450 34A and also exhibits diverse anti-tumor and anti-inflammatory activities.

应用

Bergamottin may be used as an analytical standard to test its efficacy in the following:

  • Blocker of STAT3 activation pathway in tumor cells; its potential in the therapy of multiple myeloma (MM) and other cancers is investigated.
  • Prevention and the treatment of cancer via suppression of the NF-kB signaling pathway and its regulated gene products.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

基本信息

经验(实验)分子式C21H22O4
分子量338.40
Beilstein1353914
MDL编号MFCD00017409
PubChem化学物质编号329747253
NACRESNA.24

产品性质

等级analytical standard
质量水平100
测定≥98.0% (HPLC)
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp75-80 ℃
application(s)food and beverages
格式neat
储存温度2-8℃
SMILES stringC\C(C)=C\CC\C(C)=C\COc1c2C=CC(=O)Oc2cc3occc13
InChI1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-16-7-8-20(22)25-19(16)13-18-17(21)10-12-23-18/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+
InChI keyDBMJZOMNXBSRED-OQLLNIDSSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
PHL89868Bergamottinphyproof® Reference Substance3997.36元/20 MG;   咨询

产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式C21H22O4
分子量338.40
Beilstein1353914
MDL编号MFCD00017409

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥95.0% (HPLC)
形式solid
manufacturer/tradenamePhytoLab
mp75-80 ℃
储存温度−20℃
SMILES stringC\C(C)=C\CC\C(C)=C\COc1c2C=CC(=O)Oc2cc3occc13
InChI1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-16-7-8-20(22)25-19(16)13-18-17(21)10-12-23-18/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+
InChI keyDBMJZOMNXBSRED-OQLLNIDSSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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