CAS 736175-49-8; cp-802079 hydrochloride hydrate

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CAS:

736175-49-8

英文名称:

cp-802079 hydrochloride hydrate

({3-(4-chlorophenyl)-3-[4-(thiazole-carbonyl)-phenoxy]-propyl}-methyl-amino)-acetic acid hydrochloride hydrate

n-[3-(4-chlorophenyl)-3-[4-(2-thiazolylcarbonyl)phenoxy]propyl]-n-methyl-glycine hydrochloride hydrate

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货号

品牌

产品名称

规格

包装、参考价格

PZ0148

Sigma-Aldrich

CP-802079 hydrochloride hydrate

≥98% (HPLC)

1434.12元/5 MG; 5470.48元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

CP-802079 is a potent and selective glycine transporter type 1 (GlyT1) antagonist. Antagonists of GlyT1 increase levels of glycine in the synaptic cleft and, like direct glycine site agonists, they can augment NMDAR currents and NMDAR-mediated functions. CP-802,079 significantly increases the amplitude of the NMDAR currents and LTP.

特点和优势

This compound is featured on the Glycine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式	C₂₂H₂₁ClN₂O₄S · xHCl · yH₂O
分子量	444.93 (anhydrous free base basis)
MDL编号	MFCD18452850
PubChem化学物质编号	329823733
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
manufacturer/tradename	Pfizer^®
颜色	very light brown
溶解性	DMSO: ≥20 mg/mL
创始人	Pfizer
储存温度	2-8℃
SMILES string	O.Cl.CN(CCC(Oc1ccc(cc1)C(=O)c2nccs2)c3ccc(Cl)cc3)CC(O)=O
InChI	1S/C22H21ClN2O4S.ClH.H2O/c1-25(14-20(26)27)12-10-19(15-2-6-17(23)7-3-15)29-18-8-4-16(5-9-18)21(28)22-24-11-13-30-22;;/h2-9,11,13,19H,10,12,14H2,1H3,(H,26,27);1H;1H2
InChI key	CVQXAUBKPDYXHF-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H315 - H319 - H335
预防措施声明	P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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