CAS 72252-90-5; n-methoxysuccinyl-ala-ala-pro-val-7-amido-4-methylcoumarin

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货号

品牌

产品名称

规格

包装、参考价格

E920446

MACKLIN

N-甲氧琥珀酰基-丙氨酰-丙氨酰-脯氨酰-缬氨酸-7-氨基-4-甲基香豆素

98%

1679元/25mg;

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储存：−20°C

324740

Sigma-Aldrich

Elastase Substrate V, Fluorogenic-CAS 72252-90-5-Calbiochem

Elastase Substrate V, Fluorogenic, CAS 72252-90-5, is a sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (K_m = 140 µ

1633.58元/25 MG;

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产品说明

一般描述

Sensitive fluorogenic substrate for the quantitative determination of human leukocyte (K_m = 140 µM; K_cat/K_m = 120,000 s^-1 M^-1) and porcine pancreatic elastase. Not hydrolyzed by cathepsin G. Excitation max.: ~380 nm; emission max.: ~460 nm.
Sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (K_m = 140 µM; k_cat/K_m = 120,000 M^-1 s^-1). Not hydrolysed by cathepsin G.

包装

25 mg in Plastic ampoule

生化/生理作用

Km = 140 µM; kcat/Km = 120,000 M⁻¹ s⁻¹as substrates for human leukocyte and porcine pancreatic elastase
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase

警告

Toxicity: Standard Handling (A)

序列

MeOSuc-Ala-Ala-Pro-Val-AMC

重悬

Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.

其他说明

Barrett, A.J. 1981. Methods Enzymol. 80, 581.
Castillo, M.J., et al. 1979. Anal. Biochem.99, 53.
Nakajima, K., et al. 1979. J. Biol. Chem.254, 4027.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₃₁H₄₁N₅O₉
分子量	627.69
MDL编号	MFCD00077135

产品性质

质量水平	200
测定	≥95% (HPLC) ≥95% (TLC)
形式	lyophilized solid powder
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated protect from light
颜色	white to off-white
溶解性	ethanol: 1 mg/mL DMF: 5 mg/mL DMSO: 5 mg/mL
荧光	λ_ex 360-380 nm λ_em 430-460 nm
运输	ambient
储存温度	−20℃
InChI	1S/C31H41N5O9/c1-16(2)27(34-20-9-10-21-17(3)14-26(39)45-23(21)15-20)30(42)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11-12-25(38)44-6/h9-10,14-16,18-19,22,27,34H,7-8,11-13H2,1-6H3,(H,32,37)(H,33,40)(H,35,41,42)/t18-,19-,22-,27-/m0/s1
InChI key	NHMQNKPYBPDCAY-NFHWZJRKSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

M9771

Sigma-Aldrich

N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin

elastase substrate

4417.55元/5 MG; 23155元/50 MG;

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产品说明

应用

N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin has been used as a substrate in elastase assay using bone marrow lysates and pancreatic lysates.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

底物

Fluorogenic substrate for the assay of human leukocyte and porcine pancreatic elastase.

基本信息

经验(实验)分子式	C₃₁H₄₁N₅O₉
分子量	627.69
MDL编号	MFCD00077135
PubChem化学物质编号	24897367
NACRES	NA.32

产品性质

质量水平	200
测定	≥98% (HPLC)
形式	powder
溶解性	chloroform: 50 mg/mL, clear, colorless
储存温度	−20℃
SMILES string	COC(=O)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2
InChI	1S/C31H41N5O9/c1-16(2)27(30(42)34-20-9-10-21-17(3)14-26(39)45-23(21)15-20)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11-12-25(38)44-6/h9-10,14-16,18-19,22,27H,7-8,11-13H2,1-6H3,(H,32,37)(H,33,40)(H,34,42)(H,35,41)
InChI key	CMEUDEVBFFPSEI-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)