CAS 71997-32-5; cordycepin 5'-triphosphate sodium

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CAS:

71997-32-5

分子式:

C10H16N5O12P3

分子量:

491.18

英文名称:

cordycepin 5'-triphosphate sodium

用途:

虫草素 5′-三磷酸盐通过 poly (A) 聚合酶掺入核酸中。因为它缺少一个 3′-羟基链的产生，它可用于 3′-RNA 的末端标记。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

C921667

MACKLIN

5′-三磷酸虫草素钠盐

95%

3888元/1mg;

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储存：−20°C
状态：白色粉末

C9137

Sigma-Aldrich

Cordycepin 5′-triphosphate sodium salt

≥95%

2154.4元/1 MG; 8197.44元/5 MG;

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产品说明

一般描述

Cordycepin (3′-deoxyadenosine) is a cytotoxic adenosine analog and a bioactive agent extracted from Cordyceps militaris. Cordycepin 5′-triphosphate is a toxic derivative of cordycepin.

应用

Cordycepin 5′-triphosphate sodium salt has been used:

as a transcriptional inhibitor in RNA decay assay
to inhibit polyadenylation in HEK293T cells before harvesting for in- vitro interaction studies through co-immunoprecipitation (co-Ips)
as a positive control in in vitro assays for polymerase inhibition
as a precursor to produce cordycepin monophosphate

包装

1, 5 mg in glass bottle

生化/生理作用

Cordycepin exhibits various metabolic effects by activating AMP-activated protein kinase (AMPK) in humans. Cordycepin triphosphate inhibits picornavirus polymerase-specific RNA synthesis by blocking in vitro [3H]GMP incorporation. It also retards cell growth by inhibiting RNA synthesis.
虫草素 5′-三磷酸盐通过 poly (A) 聚合酶掺入核酸中。因为它缺少一个 3′-羟基链的产生，它可用于 3′-RNA 的末端标记。

基本信息

经验(实验)分子式	C₁₀H₁₆N₅O₁₂P₃
分子量	491.18
MDL编号	MFCD00057015
PubChem化学物质编号	24893135
NACRES	NA.51

产品性质

质量水平	200
测定	≥95%
储存温度	−20℃
SMILES string	[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)CC3O
InChI	1S/C10H16N5O12P3.Na.H/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(16)1-5(25-10)2-24-29(20,21)27-30(22,23)26-28(17,18)19;;/h3-6,10,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);;
InChI key	FRGBONDYLMUOMH-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H332 - H315 - H319 - H335 - H351
预防措施声明	P202 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
危险分类	Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
个人防护装备	Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

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