| CAS: | 71897-07-9 | |
| 分子式: | C16H14N2 | |
| 分子量: | 234.30 | |
| 英文名称: |
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| 用途: | AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG 1295 reduces neointimal formation in aortic allograft vasculopathy by inhibition of PDGFR-beta-trig |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||
| A911472 | MACKLIN | AG 1295 | 98% | 495元/5mg; 1665元/25mg; | 咨询 | ||||||||||||||||||||||||||||||||
储存：-20°C，密闭，干燥 | |||||||||||||||||||||||||||||||||||||
| 658550 | Sigma-Aldrich | AG 1295-CAS 71897-07-9-Calbiochem | A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC₅₀ = 500 nM) and PDGF-dependent DNA synthesis (IC₅& | 1954.93元/5 MG; | 咨询 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 µM) in Swiss/3T3 cells. Has no effect on EGF receptor autophosphorylation and shows only a weak effect on EGF- or insulin-stimulated DNA synthesis. A potent blocker of smooth muscle cell proliferation. 包装 5 mg in Plastic ampoule 生化/生理作用 Cell permeable: yes 警告 Toxicity: Standard Handling (A) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. 其他说明 Banai, S., et al. 1998. Circulation 97, 1960. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
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