CAS 71865-37-7; dtme (dithio-bis-maleimidoethane)

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

B868603

MACKLIN

双(2-马来酰亚胺基乙基)二硫化物

98%

823元/25mg;

咨询

储存：-20°C
状态：白色到浅黄色粉末到晶体

B5699

TCI

Bis(2-maleimidoethyl) Disulfide

>98.0%(HPLC)(N)

1560元/25MG; 4190元/100MG;

咨询

基本信息

纯度/分析方法	>98.0%(HPLC)(N)
分子式/分子量	C₁₂H₁₂N₂O₄S₂ = 312.36
外观与形状(20℃)	固体
储存温度	-20℃
储存在惰性气体下	存放于惰性气体之中
应避免的情况	空气,加热
Reaxys-RN	1487163
PubChem物质ID	354335610
MDL编号	MFCD01863385

技术规格

Appearance	White to Light yellow powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(with Total Nitrogen)	min. 98.0 %
Melting point	120.0 to 124.0 ℃

物性(参考值)

熔点

122 ℃

安全信息

图形或危害标志
信号词	警告
危险性说明	H315 : 造成皮肤刺激。 H319 : 造成严重眼刺激。
防范说明	P264 : 作业后彻底清洗皮肤。 P280 : 戴防护手套/戴防护眼罩/戴防护面具。 P302 + P352 : 如皮肤沾染：用水充分清洗。 P337 + P313 : 如仍觉眼刺激：求医/就诊。 P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。 P332 + P313 : 如发生皮肤刺激：求医/就诊。

803618

Sigma-Aldrich

DTME (Dithio-bis-maleimidoethane)

3675.23元/50 MG;

咨询

产品说明

一般描述

DTME is a homobifunctional, maleimide crosslinker for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e., oligomerization) or protein interactions. DTME is similar in length to BMH but differs in containing a disulfide bond in its spacer arm, allowing crosslinks with DTME to be cleaved with reducing agent such as dithiothreitol (DTT).

特点和优势

Reactive groups: maleimide (both ends)
Reactive towards: sulfhydryl groups
Long (13.3A), cleavable, sulfhydryl-to-sulfhydryl crosslinker, composed of maleimide groups and 11-atom disulfide spacer arm
Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
Cleavable by reduction of disulfide spacer arm with DTT, TCEP or other reducing agent

注意

This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.

基本信息

经验(实验)分子式	C₁₂H₁₂N₂S₂O₄
分子量	312.36
MDL编号	MFCD01863385
PubChem化学物质编号	329768821
NACRES	NA.22

产品性质

质量水平	100
测定	≥90%
形式	powder
分子量	312.37
reaction suitability	reagent type: cross-linking reagent
储存条件	desiccated
溶解性	DMSO or DMF: soluble
运输	ambient
储存温度	2-8℃
SMILES string	O=C(C=CC1=O)N1CCSSCCN2C(C=CC2=O)=O
InChI	1S/C12H12N2O4S2/c15-9-1-2-10(16)13(9)5-7-19-20-8-6-14-11(17)3-4-12(14)18/h1-4H,5-8H2
InChI key	SGVWDRVQIYUSRA-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H315 - H319 - H335
预防措施声明	P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable