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CAS: 71-63-6
分子式: C41H64O13
分子量: 764.95
熔点: 228-230℃
中文名称: 
二硫胺
洋地黄毒甙
毛地黄毒甙
毛地黄毒素
地芰毒
狄吉妥辛
英文名称: 
Digtoxoside
3-[(O-2,6-Dideoxy-D-ribo-hex-opyranosyl-(14)-O-2,6-dideoxy-D-ribo-hexopy-ransyl-(14)-2,6-dideoxy-Dribo-hexopyranosyl)oxy]-14-
digitoxin
(3beta,5beta)-3-((o-2,6-dideoxy-beta-d-ribohexopyranosyl-(1-4)-o-2,6-dideoxy-be
t a-d-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-d-ribo-hexopyranosyl)oxy)-14-hy
dro xycard-20(22)- enolide
acedoxin
asthenthilo
(3beta,5beta)-y)-14-hydroxy
3-[(o-2,6-dideoxy- beta-d-ribo-hexopyranosyl-(1.fwdarw.4)-card-20(22)-enolid
6-dideoxy- beta-d-ribo-o-6-dideoxy- beta-d-ribo-hexopyranosyl-(1.fwdarw.4)-2
(3 beta,5 beta)-hexopyranosyl)oxy]-14-hydroxy
cardidigin
cardigin
carditalin
carditoxin
coramedan
cristapurat
crystalline digitalin
crystodigin
digicor
digilong
digimed
digimerck
digipural
digisidin
digitalin
digitalin, crystalline
digitaline cristallisee
digitaline nativelle
digitalinum verum
digitoksim
digitophyllin
digitoxigenin tridigitoxoside
digitoxigenin-tridigitoxosid
digitoxinum
digitoxoside
digitrin
ditaven
glucodigin
lanatoxin
mono-digitoxid
mono-glycocard
monodigitoxoside
myodigin
purodigin
purpurid
tardigal
tri-digitoxoside
unidigin
展开更多英文名
性质描述: 白色或类白色结晶性粉末。熔点256-257℃。溶于酸、氯仿、丙酮和吡啶,微溶于水及石油醚。无臭,味苦。从稀醇中结晶常含有半分子或一分子结晶水或结合一分子乙醇。真空加热至118℃可转为无水物。
生产方法: 自然界中,洋地黄叶及其他强心性生药的有效成分为甾体粮甙,动物中蟾蜍的分泌物中也含有同类的物质。洋地黄毒甙分子中,糖结合顺洋地黄毒甙配套([143-62-4])C3的羟基上。粮苷配基带有丁烯内酯结构。医药工业中,将洋地黄叶粉加水在28-35℃发醇,用70%乙醇提取发酵叶粉,浓缩、过滤。取浓缩液在28-30℃去胶4-6h,再用氯仿提取。提取液依次用水、5%氢氧化钠溶液、水洗涤,浓缩至粘稠状,加无水丙酮结晶,在0-5℃放置过夜,过滤得湿品。再经柱上层析精制和洋地黄毒甙。
用途: 该品与地高辛(异羟基洋地黄毒甙)相同,能加强心肌收缩力,减慢心率和抑制传导。其特点是作用开始慢而持久,适用于慢性心功能不全患者长期服用。该品不可与酸碱类药物配伍。该品对豚鼠、猫的口服LD50分别为60.0和0.18mg/kg。
推荐供应商
货号品牌产品名称规格包装、参考价格
D860643MACKLIN洋地黄毒苷98%38元/1mg;   99元/5mg;   250元/25mg;   961元/100mg;   咨询
储存:-20°C
状态:白色到灰白色粉末
D5878Sigma-AldrichDigitoxin≥92% (HPLC), powder1267.92元/250 MG;   2134.97元/500 MG;   3686.87元/1 G;   12725.6元/5 G;   21862.4元/10 G;   咨询

产品说明

一般描述

洋地黄毒苷是一种强心苷(CG)。它是一种强心药,表现出心脏 和抗癌特性。洋地黄毒苷可抑制核因子κB(NF-κB)信号转导。它可用于治疗充血性心力衰竭和心律不齐。洋地黄毒苷可以防止微管形成。

应用

洋地黄毒苷已被用作人类血清白蛋白(HSA)上结合位点的标记药物。它还已被用于测定其抗传播性胃肠炎病毒(TGEV)的活性。

包装

1, 5, 10 g in glass bottle
250, 500 mg in glass bottle

基本信息

经验(实验)分子式C41H64O13
分子量764.94
Beilstein76678
EC 号200-760-5
MDL编号MFCD00003686
PubChem化学物质编号24893976
NACRESNA.77

产品性质

质量水平200
测定≥92% (HPLC)
形式powder
mp240 ℃ (dec.) (lit.)
溶解性chloroform: soluble
SMILES string[H][C@@]1(C[C@H](O)[C@H](O[C@@]2([H])C[C@H](O)[C@H](O[C@@]3([H])C[C@H](O)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]4CC[C@@]5(C)[C@]([H])(CC[C@]6([H])[C@]5([H])CC[C@]7(C)[C@]([H])(CC[C@]67O)C8=CC(=O)OC8)C4
InChI1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1
InChI keyWDJUZGPOPHTGOT-XUDUSOBPSA-N
Gene Informationhuman ... ATP1A1(476), ATP1A2(477), ATP1A3(478), ATP1A4(480), ATP1B1(481), ATP1B2(482), ATP1B3(483), FXYD2(486)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 - H331 - H373
预防措施声明P260 - P264 - P270 - P301 + P310 - P304 + P340 + P311 - P314
危险分类Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
D1800000DigitoxinEuropean Pharmacopoeia (EP) Reference Standard1259.15元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C41H64O13
分子量764.94
Beilstein76678
MDL编号MFCD00003686
PubChem化学物质编号329798710
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp240 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES string[H][C@@]1(C[C@H](O)[C@H](O[C@@]2([H])C[C@H](O)[C@H](O[C@@]3([H])C[C@H](O)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]4CC[C@@]5(C)[C@]([H])(CC[C@]6([H])[C@]5([H])CC[C@]7(C)[C@]([H])(CC[C@]67O)C8=CC(=O)OC8)C4
InChI1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1
InChI keyWDJUZGPOPHTGOT-XUDUSOBPSA-N
Gene Informationhuman ... ATP1A1(476), ATP1A2(477), ATP1A3(478), ATP1A4(480), ATP1B1(481), ATP1B2(482), ATP1B3(483), FXYD2(486)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 - H331 - H373
预防措施声明P260 - P264 - P270 - P301 + P310 - P304 + P340 + P311 - P314
危险分类Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
Y0002036Digitoxin for LC assayEuropean Pharmacopoeia (EP) Reference Standard1313.88元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C41H64O13
分子量764.94
Beilstein76678
MDL编号MFCD00003686

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp240 ℃ (dec.) (lit.)
格式neat
储存温度2-8℃
SMILES string[H][C@@]1(C[C@H](O)[C@H](O[C@@]2([H])C[C@H](O)[C@H](O[C@@]3([H])C[C@H](O)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]4CC[C@@]5(C)[C@]([H])(CC[C@]6([H])[C@]5([H])CC[C@]7(C)[C@]([H])(CC[C@]67O)C8=CC(=O)OC8)C4
InChI1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1
InChI keyWDJUZGPOPHTGOT-XUDUSOBPSA-N
Gene Informationhuman ... ATP1A1(476), ATP1A2(477), ATP1A3(478), ATP1A4(480), ATP1B1(481), ATP1B2(482), ATP1B3(483), FXYD2(486)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 - H331 - H373
预防措施声明P260 - P264 - P270 - P301 + P310 - P304 + P340 + P311 - P314
危险分类Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
PHL82516Digitoxinphyproof® Reference Substance3997.36元/25 MG;   咨询

产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式C41H64O13
分子量764.94
Beilstein76678
MDL编号MFCD00003686

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥95.0% (HPLC)
manufacturer/tradenamePhytoLab
mp240 ℃ (dec.) (lit.)
格式neat
SMILES string[H][C@@]1(C[C@H](O)[C@H](O[C@@]2([H])C[C@H](O)[C@H](O[C@@]3([H])C[C@H](O)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]4CC[C@@]5(C)[C@]([H])(CC[C@]6([H])[C@]5([H])CC[C@]7(C)[C@]([H])(CC[C@]67O)C8=CC(=O)OC8)C4
InChI1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1
InChI keyWDJUZGPOPHTGOT-XUDUSOBPSA-N
Gene Informationhuman ... ATP1A1(476), ATP1A2(477), ATP1A3(478), ATP1A4(480), ATP1B1(481), ATP1B2(482), ATP1B3(483), FXYD2(486)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 - H331 - H373
预防措施声明P260 - P264 - P270 - P301 + P310 - P304 + P340 + P311 - P314
危险分类Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
BP855DigitoxinBritish Pharmacopoeia (BP) Reference Standard1259.15元/250 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 250 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C41H64O13
分子量764.94
Beilstein76678
EC 号200-760-5
MDL编号MFCD00003686
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
mp240 ℃ (dec.) (lit.)
格式neat
储存温度2-8℃
SMILES string[H][C@@]1(C[C@H](O)[C@H](O[C@@]2([H])C[C@H](O)[C@H](O[C@@]3([H])C[C@H](O)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]4CC[C@@]5(C)[C@]([H])(CC[C@]6([H])[C@]5([H])CC[C@]7(C)[C@]([H])(CC[C@]67O)C8=CC(=O)OC8)C4
InChI1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1
InChI keyWDJUZGPOPHTGOT-XUDUSOBPSA-N
Gene Informationhuman ... ATP1A1(476), ATP1A2(477), ATP1A3(478), ATP1A4(480), ATP1B1(481), ATP1B2(482), ATP1B3(483), FXYD2(486)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 - H331 - H373
预防措施声明P260 - P264 - P270 - P301 + P310 - P304 + P340 + P311 - P314
危险分类Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
1199002USPDigitoxinUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C41H64O13
分子量764.94
Beilstein76678
EC 号200-760-5
MDL编号MFCD00003686
PubChem化学物质编号329749588
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp240 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES string[H][C@@]1(C[C@H](O)[C@H](O[C@@]2([H])C[C@H](O)[C@H](O[C@@]3([H])C[C@H](O)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]4CC[C@@]5(C)[C@]([H])(CC[C@]6([H])[C@]5([H])CC[C@]7(C)[C@]([H])(CC[C@]67O)C8=CC(=O)OC8)C4
InChI1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1
InChI keyWDJUZGPOPHTGOT-XUDUSOBPSA-N
Gene Informationhuman ... ATP1A1(476), ATP1A2(477), ATP1A3(478), ATP1A4(480), ATP1B1(481), ATP1B2(482), ATP1B3(483), FXYD2(486)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 - H331 - H373
预防措施声明P260 - P264 - P270 - P301 + P310 - P304 + P340 + P311 - P314
危险分类Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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