| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |
| M813348 | MACKLIN | α-甲基-L-酪氨酸 | 98% | 154元/100mg; 303元/250mg; 742元/1g; | 咨询 |
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| M8131 | Sigma-Aldrich | α-Methyl-L-tyrosine | ≥98% (TLC) | 1361.39元/100 MG; 2836.12元/250 MG; 8319.88元/1 G; 32819元/5 G; | 咨询 |
产品说明 应用 α-甲基-L-酪氨酸可被用于确定Fe2/甲基苯丙胺(METH)介导的细胞死亡是否依赖于胞质多巴胺和铁介导的氧化应激。
α-甲基-L-酪氨酸已作为酪氨酸羟化酶抑制剂而用于： - 在斑马鱼急性应激期间检测其作用
- 在大麻素受体1型(CB1)基因敲除和野生型小鼠中检测其对去甲肾上腺素周转的影响
- 在大鼠脾脏样品中检测儿茶酚胺缺失对应激的影响
- 在多巴胺能神经元中阻断多巴胺的合成
包装 1, 5 g in poly bottle
100, 250 mg in poly bottle 生化/生理作用 α-甲基-L-酪氨酸(L-AMPT)可作为酪氨酸羟化酶的一种竞争性抑制剂并对酪氨酸向L-DOPA的转化进行抑制，最终降低细胞质中多巴胺的合成。低浓度的AMPT可用作难治性肌张力障碍或运动障碍的一种有效疗法。它还有助于降低嗜铬细胞瘤患者中的儿茶酚胺浓度。
酪氨酸羟化酶抑制剂。 其他说明 活性异构体 基本信息 | 经验(实验)分子式 | C10H13NO3 | | 分子量 | 195.22 | | Beilstein | 2368400 | | EC 号 | 211-599-5 | | MDL编号 | MFCD00064201 | | PubChem化学物质编号 | 24278155 | | NACRES | NA.32 |
产品性质 | 测定 | ≥98% (TLC) | | 储存温度 | −20℃ | | SMILES string | C[C@](N)(Cc1ccc(O)cc1)C(O)=O | | InChI | 1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1 | | InChI key | NHTGHBARYWONDQ-JTQLQIEISA-N | | Gene Information | human ... TH(7054) |
安全信息 | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
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| 1443205 | USP | Metyrosine | United States Pharmacopeia (USP) Reference Standard | 3390元/200 MG; | 咨询 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia. 生化/生理作用 酪氨酸羟化酶抑制剂。 分析说明 These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. 其他说明 USP issued SDS can be found here.
Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C10H13NO3 | | 分子量 | 195.22 | | Beilstein | 2368400 | | MDL编号 | MFCD00064201 | | PubChem化学物质编号 | 329750462 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | USP | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | SMILES string | C[C@](N)(Cc1ccc(O)cc1)C(O)=O | | InChI | 1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1 | | InChI key | NHTGHBARYWONDQ-JTQLQIEISA-N | | Gene Information | human ... TH(7054) |
安全信息 | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 324725 | Fluorochem | (S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid | 95% | 5962元/250mg; 11924元/1g; | 咨询 |
基本信息 | CAS Number | 672-87-7 | | MDL Number | MFCD00064201 | | Melting Point | >211℃ |
安全信息 | 图形或危害标志 |  | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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