| CAS: | 6505-99-3 | ||||
| 分子式: | C13H19N5O2S2 | ||||
| 分子量: | 341.45 | ||||
| 英文名称: |
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| 用途: | JA2131 is a selective bioavailable poly(ADP-ribose) glycohydrolase (RARG) inhibitor with IC50 of 0.4 μM. |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||
| J910763 | MACKLIN | JA2131 | 95% | 19678元/5mg; | 咨询 | ||||||||||||||||||
储存：-20°C，密闭，干燥 | |||||||||||||||||||||||
| SML2968 | Sigma-Aldrich | JA2131 | ≥98% (HPLC) | 1452.63元/5 MG; 4672.46元/25 MG; | 咨询 | ||||||||||||||||||
产品说明 生化/生理作用 JA2131 is a cell penetrant, potent and selective poly(ADP-ribose) glycohydrolase (PARG) inhibitor that selectively kills cancer cells. JA2131 induces PARP1 hyper-PARylation and sensitizes cancer cells to radiation-induced DNA damage. JA2131 induces replication fork defects. 基本信息
产品性质
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