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CAS: 64987-85-5
分子式: C16H18N2O6
分子量: 334.32
熔点: 175-180℃
英文名称: 
n-(4-carboxycyclohexylmethyl)maleimide n-hydroxysuccinimide ester
n-succinimidyl 4-(maleimidome.)cyclo-hexanecarboxylate
性质描述: Chloroform: soluble 50 mg/mL   DMF: soluble
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M793332MACKLIN4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯10mM in DMSO185元/1ml;   咨询
储存:-20°C, 避光
状态:液体
M824069MACKLIN4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯98%35元/200mg;   132元/1g;   640元/5g;   2399元/25g;   6240元/100g;   咨询
储存:-20℃
状态:白色到灰白色到浅棕色黄色粉末
物化性质:Chloroform: soluble 50 mg/mL DMF: soluble
S0853TCIN-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate>98.0%(HPLC)950元/100MG;   3545元/1G;   咨询

基本信息

纯度/分析方法>98.0%(HPLC)
分子式/分子量C16H18N2O6 = 334.33
外观与形状(20℃)固体
储存温度<0℃
储存在惰性气体下存放于惰性气体之中
应避免的情况光,湿气 (分解),加热
Reaxys-RN1555271
PubChem物质ID135727275
MDL编号MFCD00009634

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Elemental analysis(Nitrogen)8.20 to 8.50 %
Melting point175.0 to 179.0 ℃

物性(参考值)

熔点177 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
U0143TCIN-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate (2mg×5)1490元/1SET;   咨询

基本信息

分子式/分子量C16H18N2O6 = 334.33
外观与形状(20℃)固体
储存温度<0℃
储存在惰性气体下存放于惰性气体之中
应避免的情况光,湿气 (分解),加热
Reaxys-RN1555271
MDL编号MFCD00009634

技术规格

AppearanceWhite to Almost white powder to crystaline
Conjugate testto pass test(confirmed reactivity with thiol and BSA)

物性(参考值)

熔点177 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
467057J&KN-Succinimidyl-4-(maleimidomethyl)cyclohexane-1-carboxylate99%817元/100MG;   1797元/250MG;   咨询

基本信息

分子式C16H18N2O6
分子量334.33
熔点176-180
MDL编码MFCD00009634
Beilstein1555271
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P280
P305+P351+P338
P304+P340
P405
P501a
M5525Sigma-Aldrich4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester≥98%, powder377.89元/5 MG;   1227.54元/25 MG;   3735.86元/100 MG;   咨询

产品说明

一般描述

4-(N-马来酰亚胺基甲基)环己烷羧酸 N-羟基琥珀酰亚胺酯(SMCC)是一种异双功能交联剂,其包含一个具有胺和巯基反应性的延长间隔基。它通常首先通过酰胺键(pH7.5(6.5-8.5)缓冲)与含有伯胺的分子进行偶联。第二次偶联通过硫醚键(pH6.8(6.5-7.0)缓冲)与含有游离巯基的分子进行特异性偶联。SMCC包含九个原子连接子。与芳族间隔基相比,延伸的脂族间隔基可在偶联之前稳定马来酰亚胺。

应用

4-(N-马来酰亚胺基甲基)环己烷羧酸 N-羟基琥珀酰亚胺酯(SMCC)可用于制备酶免疫结合物和半抗原载体分子结合物。它已用于将肽序列与氨基进行偶联。

包装

5 mg in glass bottle
25, 100 mg in poly bottle

基本信息

经验(实验)分子式C16H18N2O6
分子量334.32
Beilstein1555271
MDL编号MFCD00009634
PubChem化学物质编号24897020
NACRESNC.07

产品性质

质量水平200
测定≥98%
形式powder
reaction suitabilityreagent type: cross-linking reagent
mp180-182 ℃ (lit.)
溶解性chloroform: 50 mg/mL
DMF: soluble
运输wet ice
储存温度−20℃
SMILES stringO=C(ON1C(CCC1=O)=O)C2CCC(CN3C(C=CC3=O)=O)CC2
InChI1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
InChI keyJJAHTWIKCUJRDK-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
573114MilliporeSMCC2568.49元/100 MG;   咨询

产品说明

一般描述

Heterobifunctional reagent useful for enzyme labeling of antibodies and antibody fragments. Cross-links both a sulfhydryl group and a free amine group. Useful for sequential conjugation to minimize polymerization.
Heterobifunctional reagent useful for enzyme labeling of antibodies and antibody fragments. Reacts with primary amines and sulfhydryl groups.

包装

100 mg in Plastic ampoule

警告

Toxicity: Irritant (B)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Caruelle, D., et al. 1988. Anal. Biochem.173, 328.
Nashat, A.H., et al. 1998. Biotechnol. Bioeng.60, 137.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C16H18N2O6
分子量334.32
MDL编号MFCD00009634

产品性质

质量水平100
测定≥97% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated
颜色 white
溶解性DMF: 10 mg/mL
acetonitrile: soluble
运输ambient
储存温度−20℃
InChI1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
InChI keyJJAHTWIKCUJRDK-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
214622Fluorochem2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate95%770元/250mg;   1650元/1g;   5808元/5g;   27720元/25g;   咨询

基本信息

CAS Number64987-85-5
MDL NumberMFCD00009634

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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