CAS 6469-93-8; 2-chloro-9-(3-(dimethylamino)propylidene)-, hydrochloride, (z)-thioxanthen

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CAS:

6469-93-8

分子式:

C18H18ClNS.HCl

分子量:

352.32

英文名称:

2-chloro-9-(3-(dimethylamino)propylidene)-, hydrochloride, (z)-thioxanthen

(z)-2-chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride

(z)-chlorprothixene hydrochloride

cis-2-chloro-9-(3-(dimethylamino)propylidene)thioxanthene, hydrochloride

cis-chlorprothixene hydrochloride

chlorprothixene hydrochloride

用途:

Chlorprothixene HCl is the hydrochloride salt form of chlorprothixene, a typical antipsychotic drug of the thioxanthene (tricyclic) class. It exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.

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货号

品牌

产品名称

规格

包装、参考价格

C873669

MACKLIN

盐酸氯普噻吨

98%

388元/1g;

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储存：-20℃
状态：白色到灰白色到浅黄色粉末

C795102

MACKLIN

盐酸氯普噻吨

10mM in DMSO

620元/1ml;

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储存：-20°C

C1671

Sigma-Aldrich

Chlorprothixene hydrochloride

472.48元/1 G;

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产品说明

一般描述

Chlorprothixene is a neuroleptic drug, which belongs to thioxanthene group. It has anticholinergic effects. Chlorprothixene might be associated with obstructive jaundice and parkinsonism. It is used to treat psychosis.

应用

Chlorprothixene hydrochloride has been used to study its exposure effects on learning and memory of rats.

包装

1 g in poly bottle

生化/生理作用

D₂ dopamine receptor antagonist; blocks a subset of GABA_A receptors in rat cortex that is also blocked by clozapine; thioxanthine antipsychotic.

基本信息

经验(实验)分子式	C₁₈H₁₈ClNS · HCl
分子量	352.32
EC 号	229-289-3
MDL编号	MFCD01941605
PubChem化学物质编号	24278300
NACRES	NA.77

产品性质

质量水平	100
储存温度	2-8℃
SMILES string	Cl.CN(C)CC\C=C1\c2ccccc2Sc3ccc(Cl)cc13
InChI	1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;
InChI key	YWKRLOSRDGPEJR-KIUKIJHYSA-N
Gene Information	human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

安全信息

象形图
警示用语：	Danger
危险声明	H301
预防措施声明	P301 + P310
危险分类	Acute Tox. 3 Oral
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

C1915000

Chlorprothixene hydrochloride

European Pharmacopoeia (EP) Reference Standard

1572.27元/ ;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₈H₁₈ClNS · HCl
分子量	352.32
MDL编号	MFCD01941605
PubChem化学物质编号	329774917
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	Cl.CN(C)CC\C=C1\c2ccccc2Sc3ccc(Cl)cc13
InChI	1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;
InChI key	YWKRLOSRDGPEJR-KIUKIJHYSA-N
Gene Information	human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

安全信息

象形图
警示用语：	Danger
危险声明	H301
预防措施声明	P301 + P330 + P331 + P310
危险分类	Acute Tox. 3 Oral
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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