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CAS: 63422-71-9
分子式: C15H17N3O5·H2O
分子量: 337.33
熔点: 171℃
中文名称: 
α-[(4-乙基-2,3-二氧代-1-哌嗪基)甲酰氨基]苯乙酸
α-{[(4-乙基-2,3-二氧代-1-哌嗪基)碳酰]氨基}苯乙酸
英文名称: 
-[(4-Ethyl-2,3-dioxo-1-piperazinyl)formamido]phenylacetic acid
-(((4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)benzeneacetic acid
(2R)-2-[(4-ethyl-2,3-dioxopiperazinyl)carbonylamino]- 2-phenylacetic acid
生产方法: 用乙醇胺以溴化氢溴化,生成β-溴乙胺,然后与乙胺缩合得N-乙基乙二胺,将后者与草酸二乙酯环合生成N'-乙基-2,3-二氧代哌嗪,进而与光气作用生成N'-乙基-2,3-二氧代哌嗪甲酰氯,最后与苯甘氨酸钠反应得到该品。
用途: 氧哌嗪青霉素的前体。
推荐供应商
货号品牌产品名称规格包装、参考价格
R838067MACKLIN(R)-(-)-α-[[(4-乙基-2,3-二氧-1-哌嗪基)羰基]氨基]苯乙酸97 %36元/1g;   108元/5g;   320元/25g;   咨询
储存:室温,干燥
E0993TCI(R)-(-)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic Acid>98.0%(T)(HPLC)150元/1G;   490元/5G;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C15H17N3O5 = 319.32
外观与形状(20℃)固体
Reaxys-RN3629459
PubChem物质ID253660152
MDL编号MFCD00799536

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Specific rotation [a]20/D-64.0 to -68.0 deg(C=1,MeOH)

物性(参考值)

熔点173 ℃(dec.)
比旋光度 [α]D-66° (C=1,MeOH)
溶解性(可溶于)甲醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
336057Fluorochem(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetic acid95%572元/1g;   1914元/5g;   咨询

基本信息

CAS Number63422-71-9
MDL NumberMFCD00799536
Melting Point173℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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