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CAS: 63283-36-3
分子式: C27H44O2·H2O
分子量: 418.65
中文名称: 
25-羟基维生素d3 一水合物
25-羟基胆钙化醇
英文名称: 
25-hydroxyvitamin d3 monohydrate
性质描述: 禁配物:强氧化剂,酰基氯,酸酐
推荐供应商
货号品牌产品名称规格包装、参考价格
H811310MACKLIN25-羟基维生素D3 一水合物98%189元/1mg;   299元/5mg;   589元/10mg;   999元/25mg;   2598元/100mg;   咨询
储存:-20°C
状态:白色到淡黄色粉末或晶体
物化性质:禁配物:强氧化剂,酰基氯,酸酐
C3537TCICalcifediol Monohydrate>98.0%(HPLC)1875元/10MG;   6290元/50MG;   咨询

基本信息

纯度/分析方法>98.0%(HPLC)
分子式/分子量C27H44O2・H2O = 418.67
外观与形状(20℃)固体
相关CAS RN19356-17-3
Reaxys-RN31147571
MDL编号MFCD08600001

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(HPLC)min. 98.0 area%
Water3.0 to 5.5 %

安全信息

图形或危害标志
信号词危险
危险性说明H300 + H310 + H330 : 吞咽、皮肤接触或吸入致命。
H372 : 长期或反复接触会对器官造成损害。
H413 : 可能对水生生物造成长期持续有害影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P262 : 严防进入眼中、接触皮肤或衣服。
P271 : 只能在室外或通风良好之处使用。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服。
P284 : [在通风不足的情况下]戴呼吸防护装置。
P314 : 如感觉不适,须求医/就诊。
P361 + P364 : 立即脱掉所有沾染的衣服,清洗后方可重新使用。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P302 + P352 + P310 : 如皮肤沾染:用水充分清洗。立即呼叫急救中心/医生。
P304 + P340 + P310 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。立即呼叫急救中心/医生。
P403 + P233 : 存放在通风良好的地方。保持容器密闭。
P405 : 存放处须加锁。

运输信息

UN编号UN2811
类别6.1
包装类别 II
监管条件代码(*)
954844J&KCalcifediol Monohydrate98%1781元/10MG;   5976元/50MG;   咨询

基本信息

分子式C27H44O2·H2O
分子量418.65
熔点109-111
MDL编码MFCD08600001
Beilstein4270041
EINECS 编号242-990-9
存储条件Freezer -20℃

安全信息

图形或危害标志
提示语Danger
危险说明H300
H310
H330
H372
防范说明P260
P264
P280
P284
P301+P310
P302+P350
UN号码2811
危险分类6.1
包装等级II
WGK3
17938Sigma-Aldrich25-Hydroxyvitamin D3 Monohydrate≥99.0% (HPLC)4554.21元/1 MG;   咨询

产品说明

生化/生理作用

胆钙化醇是维生素D3的一种失活形式,它在经历各种水平的羟基化后可形成活性的维生素D3类似物。 1α-羟基维生素D3(α-骨化醇)是一种合成类似物,其可代谢为1,25-二羟胆钙化醇(维生素D3的生物活性形式)。胆钙化醇的其他类似物可由不同的羟基化产生。 25-二羟胆钙化醇是维生素D3的主要循环形式,是1α,25-二羟胆钙化醇的生理前体。该转化由25-羟基维生素D3 1-α-羟化酶(VD3 1A羟化酶)——也称为细胞色素p450 27B1 (CYP27B1)——进行催化。

包装

无底玻璃瓶。内容物包含在插入的融合锥内。

基本信息

经验(实验)分子式C27H44O2 · H2O
分子量418.65
Beilstein4270041
MDL编号MFCD00867077
eCl@ss34058003
PubChem化学物质编号57647690
NACRESNA.79

产品性质

质量水平200
生物来源synthetic
测定≥99.0% (HPLC)
形式powder or crystals
颜色 white to off-white
运输dry ice
储存温度−20℃
SMILES string[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O
InChI1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI keyJWUBBDSIWDLEOM-DTOXIADCSA-N
Gene Informationhuman ... VDR(7421)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 + H310 + H330 - H372
预防措施声明P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310 - P314
危险分类Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - STOT RE 1 Oral
储存分类代码6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
C0166000CalcifediolEuropean Pharmacopoeia (EP) Reference Standard3059.63元/3 EA;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.Calcifediol is a biologically active metabolite of vitamin D. It is more hydrophilic and better absorbed in the intestine when compared to ergocalciferol or cholecalciferol due to the high affinity for the vitamin-D-binding protein. The drug is known to treat diseases associated with decreased intestinal absorption and obesity.

包装

Unit quantity: 5 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C27H44O2 · H2O
分子量418.65
Beilstein4270041
MDL编号MFCD00867077
PubChem化学物质编号329774765
NACRESNA.24

产品性质

生物来源sheep wool (grease)
等级pharmaceutical primary standard
agencyEP
形式solid
manufacturer/tradenameEDQM
technique(s)gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)pharmaceutical (small molecule)
格式neat
SMILES string[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O
InChI1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI keyJWUBBDSIWDLEOM-DTOXIADCSA-N
Gene Informationhuman ... VDR(7421)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 + H310 + H330 - H372
预防措施声明P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310 - P314
危险分类Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - STOT RE 1 Oral
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR2359SupelcoCalcifediolPharmaceutical Secondary Standard; Certified Reference Material6485.22元/100 MG;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC4349 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C27H44O2 · H2O
分子量418.65
Beilstein4270041
MDL编号MFCD00867077

产品性质

等级certified reference material
pharmaceutical secondary standard
形式powder
CofAcurrent certificate can be downloaded
包装pkg of 100 mg
药典可追溯性traceable to PhEur C0166000
traceable to USP 1086108
储存温度-10 to -25℃
SMILES string[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O
InChI1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI keyJWUBBDSIWDLEOM-DTOXIADCSA-N

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 + H310 + H330 - H372
预防措施声明P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310 - P314
危险分类Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - STOT RE 1 Oral
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1086108USPCalcifediolUnited States Pharmacopeia (USP) Reference Standard9438.35元/75 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C27H44O2 · H2O
分子量418.65
Beilstein4270041
MDL编号MFCD00867077
PubChem化学物质编号329749198
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度−20℃
SMILES string[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O
InChI1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI keyJWUBBDSIWDLEOM-DTOXIADCSA-N
Gene Informationhuman ... VDR(7421)

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 + H310 + H330 - H372
预防措施声明P260 - P262 - P280 - P301 + P330 + P331 + P310 - P302 + P352 + P310 - P304 + P340 + P310
危险分类Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - STOT RE 1 Oral
储存分类代码6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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