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CAS: 6270-63-9
分子式: C4H4N2O
分子量: 96.08
中文名称: 
2-羟基吡嗪
英文名称: 
2-Hydroxypyrazine
性质描述: 结晶体。熔点185-186℃。
生产方法: 氯乙酸甲酯用氨水胺化,再与乙二醛环合制得2-羟基吡嗪。将氨水冷却至0℃以下,滴加氯乙酸甲酯,保温2h。于20℃以下通氨至规定量,静置反应8h后,排除余氨,升温至60℃,减压浓缩至反应液相对密度达1.08(50℃),得氨基乙酰胺盐酸盐。反应液冷却至0℃,并保持0℃以下依次滴加氢氧化钠溶液与乙二醛,加毕,反应30min,于25℃保温2h,减压浓缩,冷却结晶,过滤,干燥,得2-羟基吡嗪钠。收率67%。
用途: 磺胺药的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
P826215MACKLINPyrazin-2-ol97%30元/1g;   124元/5g;   602元/25g;   咨询
储存:2~8℃
状态:灰白色-红黄色-棕色-黑色晶体-粉末
H1580TCI2-Hydroxypyrazine>98.0%(GC)(T)390元/1G;   咨询

基本信息

纯度/分析方法>98.0%(GC)(T)
分子式/分子量C4H4N2O = 96.09
外观与形状(20℃)固体
Reaxys-RN742009
MDL编号MFCD00233966

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(GC)min. 98.0 %
Purity(Neutralization titration)min. 98.0 %
Melting point185.0 to 189.0 ℃

物性(参考值)

熔点186 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
Y11201Alfa Aesar2-Hydroxypyrazine450元/5g;   1692元/25g;   咨询

基本信息

分子量
96.09

740152Sigma-Aldrich2-Hydroxypyrazine97%154.12元/1 G;   咨询

基本信息

经验(实验)分子式C4H4N2O
分子量96.09
EC 号228-455-2
MDL编号MFCD00233966
PubChem化学物质编号329764959
NACRESNA.22

产品性质

质量水平100
测定97%
mp185-190 ℃
SMILES stringOc1cnccn1
InChI1S/C4H4N2O/c7-4-3-5-1-2-6-4/h1-3H,(H,6,7)
InChI keyHUTNOYOBQPAKIA-UHFFFAOYSA-N

安全信息

象形图GHS05GHS07
警示用语:Danger
危险声明H302 - H318
预防措施声明P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
危险分类Acute Tox. 4 Oral - Eye Dam. 1
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
076215Fluorochem2-Hydroxypyrazine95%286元/1g;   1320元/5g;   2244元/10g;   5236元/25g;   咨询

基本信息

CAS Number6270-63-9
MDL NumberMFCD00233966
Melting Point185 - 190 ℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H318: Causes serious eye damage.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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