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CAS: 599-04-2
分子式: C6H10O3
分子量: 130.14
沸点: 120-122℃
熔点: 88-92℃
中文名称: 
(R)-3-羟基-4,4-二甲基-二氢-2(3H)-呋喃酮
泛酰内酯
二氢-3-羟基-4,4-二甲基-2(3H)呋喃酮
α-羟基-β,β-二甲基-γ-丁内酯
泛解酸内酯
英文名称: 
2(3H)-Furanone,dihydro-3-hydroxy-4,4-dimethyl-,(R)-
-Hydroxy-,-dimethyl-butyrolactone
Dihydro-4,4-dimethyl-3-hydroxy-2(3H)-furanone
Pantoyl lactone
Pantoic lactone
alpha-hydroxy-beta,beta-dimethyl-gamma-butyrolactone
dihydro-3-hydroxy-4,4-dimethyl-, (R)-2(3H)-Furanone
4-dimethyl- dihydro-3-hydroxy- ( theta)-2(3h)-furanon
d(-)-pantolactone
D-(-)-Pantolactone
(R)-(-)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone
(R)-(-)-4,5-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
D-(-)-à-Hydroxy-á,á-dimethyl
D-(-)-Pantoyl Lactone
(R)-(-)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
D-(-)-2-Hydroxy-3,3-dimethyl-gamma-butyrolactone
展开更多英文名
性质描述: 吸湿性结晶(苯/石油醚,或升华得到)。熔点 80(92℃ ),沸点 130℃ /2.4kPa,易溶于水,溶于乙醇、乙醚、氯仿、二硫化碳、苯。R型熔点 92℃,[α]-50.7°(C=2.05,H2O),S型熔点 91℃,[α]+50°(C=2.00,H2O)。
生产方法: 用异丁醛与甲醛缩合,生成α,α-二甲基-β-羟基丙醛,后者与氢氰酸在氯化钙参与下进一步缩合并水解、酸化、内酯化制得该品。
用途: 混旋泛酸钙的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
D817029MACKLIND-(-)-泛酰内酯99%30元/5g;   35元/25g;   83元/100g;   408元/500g;   2015元/2.5kg;   咨询
储存:2-8°C, 惰性气体
状态:白色到几乎白色粉末到晶体
折射率:-50.8 ° (C=2, H2O)
D793061MACKLIND-(-)-泛酰内酯10mM in DMSO185元/1ml;   咨询
储存:-20°C, 干燥
P0011TCID-(-)-Pantolactone>98.0%(T)3990元/500G;   咨询

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C6H10O3 = 130.14
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (吸湿)
Reaxys-RN3588195
PubChem物质ID87574294
SDBS (AIST Spectral DB)10296
Merck Index (14)7013
MDL编号MFCD00005392

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Neutralization back titration)min. 98.0 %
Melting point90.0 to 94.0 ℃
Specific rotation [a]20/D-49.5 to -52.0 deg(C=2, H2O)
Solubility in Wateralmost transparency

物性(参考值)

熔点92 ℃
比旋光度 [α]D-50.8° (C=2,H2O)
139609J&KD-(-)-Pantolactone98%114元/5g;   366元/25g;   1313元/100G;   咨询

基本信息

分子式C6H10O3
分子量130.14
熔点91
沸点120-122
比旋光度([α]20D) -52° to -49° (C=2, H2O)
MDL编码MFCD00005392
Beilstein3588195
Merck14,7013
EINECS 编号209-963-3
存储条件Store at 2-8℃

安全信息

防范说明P262
WGK1
L15983Alfa AesarD-(-)-Pantolactone99%536元/5g;   1649元/25g;   咨询

基本信息

MDL
MFCD00005392

EINECS
209-963-3

分子式
C6H10O3

分子量
130.14

熔点
89-91°

沸点
120-122°/15mm

灵敏度
Keep Cold. Hygroscopic.

形态
Crystalline powder

Beilstein
80957

Merck
14,7013

安全信息

TSCA

C21814Alfa AesarD(-)-Pantolactone99%518元/5g;   1412元/25g;   5286元/100g;   咨询

基本信息

Ref#
21814

MDL
5392

分子式
C6 H10 O3

分子量
130.14

1494807USPPantolactoneUnited States Pharmacopeia (USP) Reference Standard9633.46元/500 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C6H10O3
分子量130.14
Beilstein80957
MDL编号MFCD00005392
PubChem化学物质编号329750663
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
bp120-122 ℃/15 mmHg (lit.)
mp91 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCC1(C)COC(=O)[C@@H]1O
InChI1S/C6H10O3/c1-6(2)3-9-5(8)4(6)7/h4,7H,3H2,1-2H3/t4-/m0/s1
InChI keySERHXTVXHNVDKA-BYPYZUCNSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
237817Sigma-AldrichD-(-)-Pantolactone99%211.89元/5 G;   767.7元/25 G;   咨询

产品说明

应用

D-(-)-泛内酯是多种不对称合成反应中使用的手性助剂。
它可用作合成以下物质的手性原料:

  • 昆虫性信息素 1S,2S,3R-1-乙酰氧基甲基--2,3,4,4-四甲基环戊烷。
  • (R)-8-羟基-4,7,7-三甲基-7,8-二氢环戊基[e]异吲哚-1,3(2H,6H)-二酮的(-)-对映异构体, 其是一种倍半萜烯生物碱。
  • 一种名为isofregenedadiol的双环二萜。

包装

5, 25 g in glass bottle

基本信息

经验(实验)分子式C6H10O3
分子量130.14
Beilstein80957
EC 号209-963-3
MDL编号MFCD00005392
PubChem化学物质编号24854272
NACRESNA.22

产品性质

质量水平200
测定99%
形式solid
旋光性[α]25/D −49.8°, c = 2 in H2O
bp120-122 ℃/15 mmHg (lit.)
mp91 ℃ (lit.)
SMILES stringCC1(C)COC(=O)[C@@H]1O
InChI1S/C6H10O3/c1-6(2)3-9-5(8)4(6)7/h4,7H,3H2,1-2H3/t4-/m0/s1
InChI keySERHXTVXHNVDKA-BYPYZUCNSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
Y0002109PantolactoneEuropean Pharmacopoeia (EP) Reference Standard1566.42元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C6H10O3
分子量130.14
Beilstein80957
MDL编号MFCD00005392

产品性质

manufacturer/tradenameEDQM
bp120-122 ℃/15 mmHg (lit.)
mp91 ℃ (lit.)
储存温度2-8℃
SMILES stringCC1(C)COC(=O)[C@@H]1O
InChI1S/C6H10O3/c1-6(2)3-9-5(8)4(6)7/h4,7H,3H2,1-2H3/t4-/m0/s1
InChI keySERHXTVXHNVDKA-BYPYZUCNSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
PHR1465SupelcoPantolactonePharmaceutical Secondary Standard; Certified Reference Material2411.6元/500 MG;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Pantolactone may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations by gas chromatography (GC).

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA3013 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C6H10O3
分子量130.14
Beilstein80957
EC 号209-963-3
MDL编号MFCD00005392
PubChem化学物质编号329823396

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
bp120-122 ℃/15 mmHg (lit.)
mp91 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1494807
储存温度2-8℃
SMILES stringCC1(C)COC(=O)[C@@H]1O
InChI1S/C6H10O3/c1-6(2)3-9-5(8)4(6)7/h4,7H,3H2,1-2H3/t4-/m0/s1
InChI keySERHXTVXHNVDKA-BYPYZUCNSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
337172Fluorochem(R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one95%220元/1g;   286元/10g;   506元/25g;   1474元/100g;   咨询

基本信息

CAS Number599-04-2
MDL NumberMFCD00005392
Boiling Point120-122℃
Melting Point91℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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