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关键词:       仅模糊查询
CAS: 5934-29-2
分子式: C6H12ClN3O3
分子量: 209.63
熔点: 254 °C (dec.)(lit.)
中文名称: 
L-组氨酸盐酸盐水合物
L-组氨酸盐酸盐,一水
L-组氨酸盐酸盐一水物
英文名称: 
Histidine hydrochloride monohydrate
Histidine,monohydrochloride,monohydrate,L-
monohydrochloride, monohydrate, L-Histidine
L-Histidine hydrochloride hydrate
monohydrochloride, monohydrate, l-histidin
l-histidine monohydrochloride monohydrate
L-Histidine hydrochloride,mono
l-histidine hcl,histidine hcl
l-histidine monohydrochloride,monohydrate
l-histidinehcl,histidinehcl
推荐供应商
货号品牌产品名称规格包装、参考价格
L810975MACKLINL-组氨酸盐酸盐,一水合物Ultra pure,≥99.5%(AT)35元/5g;   92元/25g;   201元/100g;   660元/500g;   2768元/2.5kg;   咨询
储存:室温
状态:白色到浅黄色粉末
L810973MACKLINL-组氨酸盐酸盐,一水合物99%49元/25g;   150元/100g;   582元/500g;   2215元/2.5kg;   咨询
储存:室温
状态:白色晶体或晶体粉末
H6224MACKLINL-组氨酸盐酸盐一水物99%生物技术级85元/25g;   262元/100g;   895元/500g;   咨询
储存:室温
状态:白色粉末或晶体
H0150TCIL-Histidine Hydrochloride Monohydrate>98.0%(T)(HPLC)165元/25G;   530元/100G;   1650元/500G;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C6H9N3O2・HCl・H2O = 209.64
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (吸湿)
Reaxys-RN4168261
PubChem物质ID87570593
Merck Index (14)4720
MDL编号MFCD00151027

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %
Specific rotation [a]20/D+8.9 to +9.6 deg(C=8, HCl(1+1))

物性(参考值)

熔点254 ℃(dec.)
比旋光度 [α]D9° (C=8,HCl(1+1))
最大吸收波长280 nm
水溶性可溶
在水中的溶解度170 g/l   20 ℃
溶解性(不溶于)乙醚,醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#MS3119000
179087J&KL-Histidine monohydrochloride monohydrate99%74元/25G;   245元/100G;   867元/500G;   咨询

基本信息

分子式C6H9N3O2·HCl·H2O
分子量209.63
熔点254
比旋光度([α]20D)+8.9° to +9.5° (C=11, 6 N HCl)
MDL编码MFCD00151027
Beilstein4168261
Merck14,4720
EINECS 编号211-438-9

安全信息

防范说明P260
P262
WGK3
RTECSMS3119000
A17627Alfa AesarL-Histidine monohydrochloride monohydrate99%353元/50g;   1205元/250g;   2120元/500g;   咨询

应用
L-Histidine monohydrochloride monohydrate is used as a precursor through histidine decarboxylase. It is also used to study the cultures of the human T-lymphoblastic leukemia cell line, modulation of apoptosis. It is also used to enhance the biosynthesis of Lovastatin by cultured aspergillus terreus. It is utilized as a single nitrogen source to probe swarming in Pseudomonas aeruginosa on agar. It is employed as a component to avoid the risk of contaminating bioproducts with adventitious viruses.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00151027

EINECS
211-438-9

分子式
C6H9N3O2?HCl?H2O

分子量
209.63 (191.62anhy)

熔点
ca 240° dec.

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water.

Beilstein
4168261

Merck
14,4720

安全信息

RTECS
MS3119000

TSCA

J17080Alfa AesarL-Histidine monohydrochloride monohydrate98+%, Thermo Scientific1338元/100g;   6755元/1kg;   咨询

基本信息

MDL
MFCD00151027

EINECS
211-438-9

分子量
209.63

熔点
ca 240° dec.

灵敏度
Ambient temperatures.

形态
Crystalline powder

Beilstein
4168261

Merck
14,4720

安全信息

RTECS
MS3119000

TSCA

C41173Alfa AesarL-Histidine Hydrochloride Monohydrate98%430元/25g;   1212元/100g;   4338元/500g;   16123元/2.5kg;   咨询

基本信息

Ref#
41173

MDL
151027

分子式
C6 H9 N3 O2 . H Cl . H2 O

分子量
209.64

BP383-100Alfa AesarL-HISTIDINE.HCL.H20 100G658元/100g;   咨询

基本信息

Ref#
F53466

H8125Sigma-AldrichL-Histidine monohydrochloride monohydrate≥98% (HPLC)374.97元/5 G;   401.36元/25 G;   1302.61元/100 G;   8977.25元/1 KG;   25022.6元/5 KG;   咨询

产品说明

应用

L- 组氨酸单盐酸盐一水合物已被用作发酵液的组分,以匹配金枪鱼肉的氨基酸组成。它还用于在拟南芥种子发育期间部分拯救IMPL2(肌醇单磷酸酶)表型。

包装

5, 25, 100 g in poly bottle
1 kg in poly bottle
5 kg in poly drum

生化/生理作用

组氨酸可参与蛋白质甲基化。它与血红蛋白的结构和功能有关。组氨酸存在于抗氧化二肽中。它涉及单碳单位的代谢过程。

基本信息

经验(实验)分子式C6H9N3O2 · HCl · H2O
分子量209.63
Beilstein4168261
MDL编号MFCD00151027
eCl@ss32160406
PubChem化学物质编号57654272
NACRESNA.32

产品性质

质量水平200
测定≥98% (HPLC)
mp254 ℃ (dec.) (lit.)
溶解性H2O: 50 mg/mL, clear, colorless to very faintly yellow
SMILES stringO.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI keyCMXXUDSWGMGYLZ-XRIGFGBMSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
H5659Sigma-AldrichL-Histidine monohydrochloride monohydratefrom non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%594.92元/25 G;   1528元/100 G;   8799.43元/1 KG;   咨询

产品说明

应用

非动物源性L-组氨酸盐酸盐被用于生物制造用细胞培养基配方中。 使用非动物来源的L-组氨酸和其他成分可避免外来病毒污染生物制品的风险。
L-组氨酸盐酸盐水合物已可用于蜜蜂细胞培养基中。

包装

25, 100 g in poly bottle
1 kg in poly bottle

生化/生理作用

L-组氨酸参与一碳单位代谢。它与蛋白质甲基化有关。L-组氨酸是血红蛋白结构和功能的一部分。L-组氨酸是具有抗氧化性的二肽的组分。组氨酸是组胺形成的前体,与过敏反应有关。尿酸是皮肤的免疫反应调节剂,它也是由组氨酸生物合成的。

基本信息

经验(实验)分子式C6H9N3O2 · HCl · H2O
分子量209.63
Beilstein4168261
MDL编号MFCD00151027
eCl@ss32160406
PubChem化学物质编号24895703
NACRESNA.26

产品性质

质量水平200
生物来源non-animal source
agencymeets EP testing specifications
产品线BioXtra
测定98.5-101.0%
形式crystalline powder
technique(s)cell culture | mammalian: suitable
杂质 endotoxin, tested
颜色 white
mp254 ℃ (dec.) (lit.)
溶解性H2O: 100 mg/mL
web metadata keyword.defaultL-amino acid, active isomer, non-essential amino acid, charged polar side-chain
SMILES stringO.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI keyCMXXUDSWGMGYLZ-XRIGFGBMSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
53370Sigma-AldrichL-Histidine monohydrochloride monohydrate≥99.0% (AT)405.62元/25 G;   1285.07元/100 G;   3978.12元/500 G;   咨询

产品说明

一般描述

L-组氨酸是一种亲水性必需氨基酸,其具有含有咪唑基的碱性侧链。

生化/生理作用

L-组氨酸可由ATP、5-磷酸核糖-1-焦磷酸(PRPP)和谷氨酰胺生物合成。这种必需氨基酸可被组氨酸酶、尿苷酶和咪唑酮丙酸酶降解为谷氨酸;它也是组氨酸脱羧酶作用的组胺前体。

基本信息

经验(实验)分子式C6H9N3O2 · HCl · H2O
分子量209.63
Beilstein4168261
MDL编号MFCD00151027
PubChem化学物质编号329757872
NACRESNA.77

产品性质

质量水平100
测定≥99.0% (AT)
旋光性[α]20/D +9.5±0.5°, c = 5% in 5 M HCl
杂质≤0.3% foreign amino acids
mp254 ℃ (dec.) (lit.)
溶解性H2O: 1 g/10 mL, clear, colorless (hot)
痕量阴离子sulfate (SO42-): ≤100 mg/kg
痕量阳离子Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
NH4+: ≤500 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
SMILES stringO.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI keyCMXXUDSWGMGYLZ-XRIGFGBMSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
H4036SAFCL-Histidine monohydrochloride monohydrate2991.11元/100 G;   11849.2元/1 KG;   64949元/10 KG;   咨询

产品说明

一般描述

如需获取此产品的相关文档,请联系客户支持并选择“产品文档”。请注意,需要签署保密协议才能获取该产品相关文档。

应用

L-组氨酸,一种必需氨基酸。它在治疗性重组蛋白和单克隆抗体的商业生物制造中用作细胞培养基组分。L-组氨酸单盐酸盐一水合物是 L-组氨酸的改进形式,具有改善的溶解性。

基本信息

经验(实验)分子式C6H9N3O2 · HCl · H2O
分子量209.63
Beilstein4168261
MDL编号MFCD00151027
eCl@ss32160406
PubChem化学物质编号57654249
NACRESNA.26

产品性质

生物来源non-animal source
测定≥98.5%
形式powder
manufacturer/tradenameAjinomoto
technique(s)cell culture | mammalian: suitable
杂质 endotoxin, heavy metals, residual solvents, tested
mp254 ℃ (dec.) (lit.)
溶解性H2O: 50 mg/mL
application(s)pharmaceutical (small molecule)
异质活性cytotoxicity, tested
SMILES stringO.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI keyCMXXUDSWGMGYLZ-XRIGFGBMSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
1.04350MilliporeL-Histidine monohydrochloride monohydratefor biochemistry457.28元/25 G;   1203.1元/100 G;   3355.38元/500 G;   34084.1元/10 KG;   咨询

产品说明

分析说明

Assay (alkalimetric, calculated on dried substance): ≥ 99.0 %
Identity (IR-spectrum): passes test
Appearance: white to almost white crystalline powder or colorless crystals
Appearance of solution (50 g/l CO₂-free water): clear and colorless
Spec. rotation (α 20/D, 110 g/l, hydrochloric acid 120 g/l, calc. on dried substance): +9.2 to +10.6
Sulfate (SO₄): ≤ 0.02 %
Heavy metals (as Pb): ≤ 0.001 %
As (Arsenic): ≤ 0.0005 %
Ca (Calcium): ≤ 0.001 %
Co (Cobalt): ≤ 0.0005 %
Fe (Iron): ≤ 0.0005 %
K (Potassium): ≤ 0.0005 %
Mg (Magnesium): ≤ 0.0005 %
Na (Sodium): ≤ 0.005 %
NH₄ (Ammonium): ≤ 0.01 %
Zn (Zinc): ≤ 0.0005 %
Foreign amino acids: ≤ 0.3 %
Other ninhydrine positive substances: ≤ 0.1 %
Loss on drying (150 °C): 7.0 - 10.0 %

基本信息

经验(实验)分子式C6H9N3O2 · HCl · H2O
分子量209.63
Beilstein4168261
MDL编号MFCD00151027
EC索引号211-438-9

产品性质

质量水平100
蒸汽压<1 hPa ( 20 ℃)
pH值(酸碱度)3.5-4.5 (20 ℃, 100 g/L in H2O)
mp254 ℃ (dec.) (lit.)
溶解性 149.55 g/L
密度1.49 g/cm3 at 20 ℃
堆积密度770 kg/m3
储存温度2-30℃
SMILES stringO.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI keyCMXXUDSWGMGYLZ-XRIGFGBMSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
H0755000Histidine hydrochloride monohydrateEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C6H9N3O2 · HCl · H2O
分子量209.63
Beilstein4168261
MDL编号MFCD00151027
PubChem化学物质编号329815133
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp254 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringO.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI keyCMXXUDSWGMGYLZ-XRIGFGBMSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
8.16005Sigma-Aldrich(S)-(+)-Histidine hydrochloride monohydratefor synthesis436.19元/25 G;   884.27元/100 G;   咨询

产品说明

分析说明

Assay (argentometric): ≥ 99.0 %
Spec. rotation [α²0/D (c=11 in HCl 6 mol/l): +8.5 - +9.5 °
Identity (IR): passes test

基本信息

经验(实验)分子式C6H9N3O2 · HCl · H2O
分子量209.63
Beilstein4168261
MDL编号MFCD00151027
EC索引号211-438-9

产品性质

质量水平200
蒸汽压<1 hPa ( 20 ℃)
pH值(酸碱度)3.5-4.5 (20 ℃, 100 g/L in H2O)
mp254 ℃ (dec.) (lit.)
溶解性 149.55 g/L
密度1.49 g/cm3 at 20 ℃
堆积密度770 kg/m3
储存温度2-30℃
SMILES stringO.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI keyCMXXUDSWGMGYLZ-XRIGFGBMSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
1308550USPL-Histidine monohydrochloride monohydrateUnited States Pharmacopeia (USP) Reference Standard3097.34元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C6H9N3O2 · HCl · H2O
分子量209.63
Beilstein4168261
MDL编号MFCD00151027
PubChem化学物质编号329750007
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp254 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringO.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI keyCMXXUDSWGMGYLZ-XRIGFGBMSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
450932AmethystL-Histidine monohydrochloride monohydrate99%, 用于合成63元/25G;   168元/100G;   657元/500G;   咨询

基本信息

分子式C6H9N3O2·HCl·H2O
分子量209.63
熔点254
比旋光度([α]20D)+9.2° to +10.6° (C=11, 6 N HCl)
MDL编码MFCD00151027
Beilstein4168261
Merck14,4720
EINECS 编号211-438-9

安全信息

防范说明P260
P262
WGK3
RTECSMS3119000
091488Fluorochem(S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid hydrochloride hydrate95%396元/25g;   1166元/100g;   3542元/500g;   咨询

基本信息

CAS Number5934-29-2
MDL NumberMFCD00151027

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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