CAS 59277-89-3; 阿昔洛韦; Acycolguanosine

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货号

品牌

产品名称

规格

包装、参考价格

A829547

MACKLIN

阿昔洛韦

97%

29元/1g; 35元/5g; 59元/25g; 198元/100g; 697元/500g;

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储存：2~8°C,密封
状态：白色到淡黄色晶体或粉末

A797992

MACKLIN

阿昔洛韦

10mM in DMSO

356元/1ml;

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储存：-20°C

A1915

TCI

Acyclovir

>98.0%(HPLC)

295元/1G; 460元/5G; 995元/25G;

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基本信息

纯度/分析方法	>98.0%(HPLC)
分子式/分子量	C₈H₁₁N₅O₃ = 225.21
外观与形状(20℃)	固体
Reaxys-RN	1219402
PubChem物质ID	87559875
SDBS (AIST Spectral DB)	52102
Merck Index (14)	146

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(Nonaqueous Titration)	min. 94.0 %

物性(参考值)

熔点

262 ℃

安全信息

信号词	警告
危险性说明	H316 : 造成轻微皮肤刺激。 H320 : 造成眼刺激。
防范说明	P264 : 作业后彻底清洗皮肤。 P337 + P313 : 如仍觉眼刺激：求医/就诊。 P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P332 + P313 : 如发生皮肤刺激：求医/就诊。

相关法规

RTECS#

UP0791400

134052

J&K

Acyclovir

99%, 疱疹病毒的胸苷激酶抑制剂

275元/1G; 445元/5G;

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基本信息

分子式	C₈H₁₁N₅O₃
分子量	225.21
熔点	262
MDL编码	MFCD00057880
Beilstein	1219402
Merck	14,146
存储条件	Freezer -20℃

安全信息

图形或危害标志
提示语	Warning
危险说明	H316 H320
防范说明	P264 P305+P351+P338 P332+P313 P337+P313
WGK	2
RTECS	UP0791400

R11001

Alfa Aesar

Acyclovir Standard solution

100ppm

629元/1ml;

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安全信息

危险等级
3

PHR1254

Supelco

Acyclovir

Pharmaceutical Secondary Standard; Certified Reference Material

1162.78元/1 G;

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产品说明

一般描述

用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便且高性价比的替代方案。
阿昔洛韦是一种无环鸟苷衍生物，可有效治疗单纯疱疹病毒引起的皮肤感染。

应用

阿昔洛韦可用作药物参考标准品，用于通过各种色谱技术测定血浆、血清样品和散装药物/制剂中的分析物。
这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

这些二级标准品可追溯至USP、EP(PhEur)和BP一级标准品。

其他说明

本认证参考材料是根据国际标准化组织指南17034和国际标准化组织/国际电工委员会17025生产和认证的。所有关于客户关系管理的信息都可以在分析证书上找到。

附注

想要查看本品的分析证书示例，请在下框中输入LRAC2956。这只是一个示例证书，可能与您收到的批次不符。

基本信息

经验(实验)分子式	C₈H₁₁N₅O₃
分子量	225.20
EC 号	261-685-1
MDL编号	MFCD00057880
PubChem化学物质编号	329823257
NACRES	NA.24

产品性质

质量水平	300
等级	certified reference material pharmaceutical secondary standard
CofA	current certificate can be downloaded
technique(s)	HPLC: suitable gas chromatography (GC): suitable
application(s)	pharmaceutical (small molecule)
格式	neat
药典可追溯性	traceable to BP 438 traceable to PhEur A0220000 traceable to USP 1012065
储存温度	2-30℃
SMILES string	NC1=Nc2c(ncn2COCCO)C(=O)N1
InChI	1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChI key	MKUXAQIIEYXACX-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable

A0220000

Aciclovir

European Pharmacopoeia (EP) Reference Standard

1572.27元/ ;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 75 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₈H₁₁N₅O₃
分子量	225.20
MDL编号	MFCD00057880
PubChem化学物质编号	329770584
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
SMILES string	NC1=Nc2c(ncn2COCCO)C(=O)N1
InChI	1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChI key	MKUXAQIIEYXACX-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable

1012065

USP

Acyclovir

United States Pharmacopeia (USP) Reference Standard

4085.07元/300 MG;

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产品说明

一般描述

Acyclovir is a nucleoside analogue antiviral drug. It is a highly potent inhibitor of herpes simplex virus. It is related to cytarabine, idoxuridine, trifluridine and vidarabine.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₈H₁₁N₅O₃
分子量	225.20
MDL编号	MFCD00057880
PubChem化学物质编号	329748935
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
格式	neat
SMILES string	NC1=Nc2c(ncn2COCCO)C(=O)N1
InChI	1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChI key	MKUXAQIIEYXACX-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0002242

Aciclovir for impurity C identification

CRS, European Pharmacopoeia (EP) Reference Standard

1341.2元/ ;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 0.3 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₈H₁₁N₅O₃
分子量	225.20
MDL编号	MFCD00057880

产品性质

manufacturer/tradename	EDQM
储存温度	2-8℃
SMILES string	NC1=Nc2c(ncn2COCCO)C(=O)N1
InChI	1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChI key	MKUXAQIIEYXACX-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0002245

Aciclovir for system suitability A

CRS, European Pharmacopoeia (EP) Reference Standard

1341.2元/ ;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₈H₁₁N₅O₃
分子量	225.20
MDL编号	MFCD00057880

产品性质

manufacturer/tradename	EDQM
储存温度	2-8℃
SMILES string	NC1=Nc2c(ncn2COCCO)C(=O)N1
InChI	1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChI key	MKUXAQIIEYXACX-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0002244

Aciclovir for impurity G identification

European Pharmacopoeia (EP) Reference Standard

1341.2元/ ;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 0.004 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₈H₁₁N₅O₃
分子量	225.20
MDL编号	MFCD00057880

产品性质

manufacturer/tradename	EDQM
储存温度	2-8℃
SMILES string	NC1=Nc2c(ncn2COCCO)C(=O)N1
InChI	1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChI key	MKUXAQIIEYXACX-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable

BP438

Aciclovir

British Pharmacopoeia (BP) Reference Standard

1760.91元/100 MG;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₈H₁₁N₅O₃
分子量	225.20
EC 号	261-685-1
MDL编号	MFCD00057880
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	BP
格式	neat
储存温度	2-8℃
SMILES string	NC1=Nc2c(ncn2COCCO)C(=O)N1
InChI	1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChI key	MKUXAQIIEYXACX-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable

A4669

Sigma-Aldrich

Acycloguanosine

≥99% (HPLC), powder

1714.02元/50 MG; 2846.2元/100 MG; 7876.09元/500 MG;

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产品说明

一般描述

无环鸟苷或阿昔洛韦是一种鸟苷类似物。

应用

阿昔洛韦作为I型单纯疱疹病毒抑制剂的应用实例：

作为阳性对照，通过Vero细胞毒性检测法比较蘑菇提取物的抗病毒活性
在感染研究中，检测其对人背根神经节来源神经元(HD10.6)细胞的电压门控钠离子通道(VGSC)的影响
检测其对人包皮成纤维细胞的干扰素刺激基因(ISG)表达诱导(Mx1和ISG15)的影响

包装

50, 100, 500 mg in poly bottle

生化/生理作用

阿昔洛韦是一种抗病毒药，在单纯疱疹病毒胸苷激酶(HSV-TK)的作用下变成三磷酸阿昔洛韦。它竞争性地抑制病毒DNA聚合酶。它对巨细胞病毒和EB(Epstein-Barr)病毒的疗效相对较弱。阿昔洛韦已被用来研究单纯疱疹病毒的潜伏机制。它也具有抗人免疫缺陷型病毒1(HIV-1)活性。

特点和优势

该化合物由GlaxoSmithKline开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。
这种化合物是ADME毒性研究的特色产品。点击此处发现更多特色ADME毒性产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

基本信息

经验(实验)分子式	C₈H₁₁N₅O₃
分子量	225.20
EC 号	261-685-1
MDL编号	MFCD00057880
PubChem化学物质编号	24278078
NACRES	NA.77

产品性质

质量水平	200
测定	≥99% (HPLC)
形式	powder
颜色	white
溶解性	H₂O: 0.7 mg/mL 1 M HCl: 50 mg/mL DMSO: 7 mg/mL
ε (extinction coefficient)	11.8 at 256 nm at 1 mM
作用机制	DNA synthesis \| interferes
抗生素抗菌谱	viruses
创始人	GlaxoSmithKline
SMILES string	NC1=Nc2c(ncn2COCCO)C(=O)N1
InChI	1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChI key	MKUXAQIIEYXACX-UHFFFAOYSA-N
Gene Information	human ... HV1S(3365), NP(4860)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

076300

Fluorochem

2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one

95%

242元/5g; 550元/25g; 1210元/100g;

咨询

基本信息

CAS Number	59277-89-3
MDL Number	MFCD00057880

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .