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CAS: 59-33-6
分子式: C17H23N3O·C4H4O4
分子量: 401.46
熔点: 100-104°C
中文名称: 
N-[(4-甲氧苯基)甲基]-N-(2-吡啶基)-N',N'-二甲基-乙二胺马来酸盐
英文名称: 
1,2-Ethanediamine,N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-,(Z)-2-butenedioate(1:1)
1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, (Z)-2-butenedioate (1:1)
pyrilaminemaleate
2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-pyridin maleate (1:1)
n-((4-methoxyphenyl)methyl)-n,n'-dimethyl-n-2-pyridinyl-2-ethanediamine
(z)-2-butenedioat
2-ethanediamine, n-[(4-methoxyphenyl)methyl]-n',n'-dimethyl-n-2-pyridinyl- (
2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridine bimaleate
2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridine maleate
2786 r.p. maleate
ah
anisopyradamine
anthisan maleate
antihist
diaminide maleate
mepyramine maleate
minihist
n,n-dimethyl-n'-(4-methoxybenzyl)-n'-(2-pyridyl)ethylenediamine maleate
n-dimethylaminoethyl-n-p-methoxy-alpha-aminopyridine maleate
n-p-methoxybenzyl-n'-n'-dimethyl-n-alpha-pyridylethylenediamine maleate
neo-antergan meleate
paramal
paraminyl maleate
pymafed
pyra maleate
pyranilamine maleate
pyraninyl
pyranisamine maleate
pyrilamine maleate
renstamin
stangen maleate
statomin maleate
thylogen maleate
pyrilamine maleate crystalline
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格
P796330MACKLIN马来酸吡拉明10mM in DMSO186元/1ml;   咨询
储存:-20°C
P864853MACKLIN马来酸吡拉明≥98%65元/1g;   275元/5g;   1255元/25g;   咨询
储存:室温
状态:白色到几乎白色晶体或粉末
P2369TCIPyrilamine Maleate>98.0%(T)(HPLC)245元/5G;   760元/25G;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C17H23N3O・C4H4O4 = 401.46
外观与形状(20℃)固体
应避免的情况
相关CAS RN91-84-9
Reaxys-RN3836479
PubChem物质ID354333684
Merck Index (14)7984
MDL编号MFCD00069333

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 %(total of Ion-Pair)
Purity(Nonaqueous Titration)min. 98.0 %
Melting point100.0 to 104.0 ℃

物性(参考值)

熔点102 ℃
最大吸收波长310(EtOH) nm
水溶性可溶

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#UT1225000
M0500000Mepyramine MaleateEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 600 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C17H23N3O · C4H4O4
分子量401.46
MDL编号MFCD00069333
PubChem化学物质编号329817794
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOC(=O)\C=C/C(O)=O.COc1ccc(CN(CCN(C)C)c2ccccn2)cc1
InChI1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI keyJXYWFNAQESKDNC-BTJKTKAUSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
P5514Sigma-AldrichPyrilamine maleate salt944.97元/5 G;   1387.85元/25 G;   2845.11元/100 G;   咨询

产品说明

应用

马来酸吡拉明盐已:

  • 作为 H 1 受体拮抗剂
  • 用于处理仙女水母属,然后被注射到小鼠腹腔,防止在在膜结合试验中有内源性组胺释放,
  • 从而测定 K i 值;并在比较抑制浓度 (IC 50 ) 研究中通过全细胞膜片钳技术使用

包装

5, 25, 100 g in glass bottle

生化/生理作用

马来酸吡拉明为 H1 组胺受体拮抗剂。马来酸吡拉明诱导脊椎动物睡眠。在 仙女水母属 中,它诱导浓度依赖性休眠。

特点和优势

该化合物由 Watson 开发 。要浏览其他由制药公司开发的化合物和经批准药物/候选药物的清单, 点击这里 。
该化合物的详细介绍见受体分类和信号转导手册的组胺受体页。要浏览该手册其他页,请点击此处。

基本信息

经验(实验)分子式C17H23N3O · C4H4O4
分子量401.46
EC 号200-422-7
MDL编号MFCD00069333
PubChem化学物质编号24277797
NACRESNA.77

产品性质

质量水平100
创始人Watson
SMILES stringOC(=O)\C=C/C(O)=O.COc1ccc(CN(CCN(C)C)c2ccccn2)cc1
InChI1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI keyJXYWFNAQESKDNC-BTJKTKAUSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHR1340SupelcoPyrilamine MaleatePharmaceutical Secondary Standard; Certified Reference Material855.65元/500 MG;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pyrilamine maleate is a first generation antihistamine drug, widely used to reduce all symptoms of cold and is also employed to reduce allergies both parenterally and locally.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Pyrilamine maleate may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography technique and liquid chromatography technique.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA1092 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C17H23N3O · C4H4O4
分子量401.46
EC 号200-422-7
MDL编号MFCD00069333
PubChem化学物质编号329823325

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to PhEur M0500000
traceable to USP 1588004
储存温度2-30℃
SMILES stringOC(=O)\C=C/C(O)=O.COc1ccc(CN(CCN(C)C)c2ccccn2)cc1
InChI1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI keyJXYWFNAQESKDNC-BTJKTKAUSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1588004USPPyrilamine MaleateUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C17H23N3O · C4H4O4
分子量401.46
MDL编号MFCD00069333
PubChem化学物质编号329750997
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringOC(=O)\C=C/C(O)=O.COc1ccc(CN(CCN(C)C)c2ccccn2)cc1
InChI1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI keyJXYWFNAQESKDNC-BTJKTKAUSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P301 + P312 + P330 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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