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CAS: 577778-58-6
分子式: C13H8N6
分子量: 248.24
中文名称: 
托匹司他
英文名称: 
topiroxostat
推荐供应商
货号品牌产品名称规格包装、参考价格
T795590MACKLIN托匹司他10mM in DMSO185元/1ml;   咨询
储存:-20°C
T855128MACKLIN托匹司他98%76元/1g;   310元/5g;   1100元/25g;   2978元/100g;   咨询
储存:室温,干燥
状态:白色到灰白色固体
SML3154Sigma-AldrichTopiroxostat≥98% (HPLC)780.67元/10 MG;   3157.38元/50 MG;   咨询

产品说明

生化/生理作用

Topiroxostat (FYX-051) is an orally active and potent inhibitor of xanthine oxidoreductase (XOR). It appears that inhibition of XOR by topiroxostat is due to the formation a covalent linkage to molybdenum via oxygen in the hydroxylation reaction intermediate. Also, topiroxostat displayed a potent, non-covalent inhibition of XOR. It is approved for the treatment of gout and hyperuricemia in Japan.

基本信息

经验(实验)分子式C13H8N6
分子量248.24
MDL编号MFCD17167057

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear (warmed)
储存温度2-8℃
SMILES stringN#CC1=NC=CC(C2=NNC(C3=CC=NC=C3)=N2)=C1

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
511535Fluorochem4-(3-(Pyridin-4-yl)-1H-1,2,4-triazol-5-yl)picolinonitrile0.98858元/250mg;   2090元/1g;   6248元/5g;   10406元/10g;   咨询

基本信息

CAS Number577778-58-6
MDL NumberMFCD17167057

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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