| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |
| D902511 | MACKLIN | 二乙酰一肟 | for spectrophotometric det. of urea, ≥99.0% | 66元/5g; 264元/25g; 568元/100g; 1712元/500g; | 咨询 |
储存：室温 状态：白色至淡黄色固体 物化性质：0.5g 本品加入到 10mL 水或者 10mL 乙醇中，可以形成澄清溶液 |
| D807427 | MACKLIN | 二乙酰一肟 | >98.0%(GC) | 48元/5g; 136元/25g; 371元/100g; 1186元/500g; 4846元/2.5kg; | 咨询 |
|
| D807426 | MACKLIN | 二乙酰一肟 | 试剂级, 98% | 43元/2g; 88元/10g; 143元/25g; 400元/100g; 1100元/500g; | 咨询 |
|
| B0683 | TCI | Diacetyl Monoxime | >98.0%(GC) | 505元/25G; 1075元/100G; | 咨询 |
基本信息 | 纯度/分析方法 | >98.0%(GC) | | 分子式/分子量 | C4H7NO2 = 101.11 | | 外观与形状(20℃) | 固体 | | Reaxys-RN | 605582 | | PubChem物质ID | 87563685 | | SDBS (AIST Spectral DB) | 492 | | MDL编号 | MFCD00002116 |
技术规格 | Appearance | White to Orange to Green powder to crystal | | Purity(GC) | min. 98.0 % | | Melting point | 75.0 to 77.0 ℃ |
物性(参考值) | 熔点 | 76 ℃ | | 沸点 | 186 ℃ | | 水溶性 | 可溶 | | 溶解性(可溶于) | 苯,氯仿,丙酮,乙醇,乙醚 |
相关法规 |
| A14339 | Alfa Aesar | 2,3-Butanedione monoxime | 99% | 881元/100g; 3309元/500g; 12868元/2500g; | 咨询 |
应用
2,3-Butanedione monoxime is a reversible inhibitor of myosin ATPase. It is also used as a reagent for colorimetric determination of urea. 备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents. 基本信息 MDL
MFCD00002116 EINECS
200-348-5 分子式
C4H7NO2 分子量
101.11 熔点
74-77° 沸点
185-186° 灵敏度
Hygroscopic. Keep Cold. 形态
Powder 溶解性
Soluble in water (50g/L at 20°C) Beilstein
605582 安全信息 RTECS
EK3150000 TSCA
是 |
| C15037 | Alfa Aesar | 2,3-Butanedione monoxime | 98% | 1077元/100g; 3563元/500g; 15569元/2.5kg; | 咨询 |
基本信息 Ref#
15037 MDL
2116 分子式
C4 H7 N O2 分子量
101.1 形态
White to cream powder |
| D24-100 | Alfa Aesar | DIACETYL MONOXIME REAGENT 100G | | 1277元/100g; | 咨询 |
|
| B0753 | Sigma-Aldrich | 2,3-Butanedione monoxime | ≥98% | 438.33元/25 G; 1168.11元/100 G; 4686.34元/500 G; 7009.84元/1 KG; | 咨询 |
产品说明 应用 2,3-丁二酮一肟可以用于： - 单-分子肌球蛋白v活性测定
- 转基因动物成像麻醉
- 降低肌肉纤维紧张张力
- 小鼠心肌细胞培养基成分
包装 25, 100, 500 g in poly bottle
1 kg in poly bottle 生化/生理作用 2,3-丁二酮一肟是ATP-敏感K+和Ca2+通道抑制剂。
DRK1是一种延迟整流 (Kv2.1)克隆K+ 通道，来自大鼠大脑，和基于蛋白质激酶磷酸化有相同位点，可能与官能化调节磷酸化有关。 2,3-丁二酮一肟(BDM)化学性地从许多蛋白质中移除磷酸基团。在蟾蜍卵母细胞DRK1 CRNA表达后研究它对于DRK1通道的行为。在双电极电压钳实验中，将2,3-丁二酮一肟用于浴槽抑制DRK1电流(ki = 16.6 mM, H = 0.96)速度快，而且可逆，时间过程和浴槽内溶液改变时间过程相似。DRK1电流在所有电位被抑制；电流活化，钝化和失活的时间过程没有被2,3-丁二酮一肟影响。在内面向外式膜片钳实验中，在缺少再磷酸化底物时，在细胞表面使用2,3-丁二酮一肟同样也会快速地抑制通道活性，而且可逆 (ki = 10.7 mM, H = 1.01)。这些结果和磷酸酶效应不一致，因为磷酸酶效应应该在无细胞，无ATP的膜片中不可逆的。相反，结果显示2,3-丁二酮一肟能够从膜里或膜外直接抑制DRK1通道。 基本信息 | 线性分子式 | CH3C(=NOH)COCH3 | | 分子量 | 101.10 | | Beilstein | 605582 | | EC 号 | 200-348-5 | | MDL编号 | MFCD00002116 | | PubChem化学物质编号 | 57653910 | | NACRES | NA.77 |
产品性质 | 质量水平 | 200 | | 测定 | ≥98% | | 形式 | powder | | bp | 185-186 ℃ (lit.) | | mp | 75-78 ℃ (lit.) | | SMILES string | CC(=O)\C(C)=N\O | | InChI | 1S/C4H7NO2/c1-3(5-7)4(2)6/h7H,1-2H3/b5-3+ | | InChI key | FSEUPUDHEBLWJY-HWKANZROSA-N | | Gene Information | human ... KCNB1(3745) |
安全信息 | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
|
| 31550 | Supelco | 2,3-Butanedione monoxime | for spectrophotometric det. of urea, ≥99.0% | 680.44元/25 G; 2375.59元/100 G; 11877.9元/500 G; | 咨询 |
产品说明 一般描述 2,3-丁二酮单肟 (BDM) 又名二乙酰单肟，它也是一种亲核剂，它能使有机磷酸酯中毒的乙酰胆碱酯酶去磷酸化。它也是骨骼肌肌球蛋白 II 的典型的非竞争性抑制剂，抑制化学和运动活性。 分析说明 溶解度：
0.5g 本品加入到 10mL 水或者 10mL 乙醇中，可以形成澄清溶液。
灵敏性测试：
将溶于 3mL 水和 5mL 浓盐酸的 0.05mg 尿素与 3% 的二乙酰单肟水溶液在水浴上加热 10 分钟，颜色呈淡黄色。 其他说明 用于尿素和脲基化合物比色测定的试剂 ；钴 (II)、镍 (II)、钯 (II) 和铼 (VII) 的光谱分析试剂 ；镍 (Ⅱ) 重量法测定用试剂 基本信息 | 线性分子式 | CH3C(=NOH)COCH3 | | 分子量 | 101.10 | | Beilstein | 605582 | | EC 号 | 200-348-5 | | MDL编号 | MFCD00002116 | | PubChem化学物质编号 | 329753805 | | NACRES | NA.21 |
产品性质 | 质量水平 | 100 | | 测定 | ≥98.0% (N)
≥99.0% | | 质量 | for spectrophotometric det. of urea | | technique(s) | UV/Vis spectroscopy: suitable | | 灼烧残渣 | ≤0.05% (as SO4) | | bp | 185-186 ℃ (lit.) | | mp | 75-76 ℃
75-78 ℃ (lit.) | | SMILES string | CC(=O)\C(C)=N\O | | InChI | 1S/C4H7NO2/c1-3(5-7)4(2)6/h7H,1-2H3/b5-3+ | | InChI key | FSEUPUDHEBLWJY-HWKANZROSA-N |
安全信息 | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
|
| 203984 | Sigma-Aldrich | 2,3-Butanedione 2-Monoxime-CAS 57-71-6-Calbiochem | An inhibitor of skeletal and cardiac muscle contraction. | 773.29元/500 MG; | 咨询 |
产品说明 一般描述 An inhibitor of skeletal and cardiac muscle contraction. A "chemical phosphatase" that dephosphorylates acetylcholinesterase poisoned with organophosphates. Inhibits Ca2+ currents in adult rat cervical ganglion in a reversible and dose-dependent manner (IC50 = 18.3 nM). Also shown to induce Ca2+ release from canine cardiac sarcoplasmic reticulum (SR).
An inhibitor of skeletal and cardiac muscle contraction. A general reversible inhibitor of myosin ATPase in eukaryotes. A “chemical phosphatase,” which dephosphorylates acetylcholinesterase poisoned with organophosphates. Inhibits Ca2+ currents in adult rat cervical ganglion in a reversible and dose-dependent manner (IC50 = 18.3 nM). Also shown to induce Ca2+ release from canine cardiac sarcoplasmic reticulum (SR). 包装 500 mg in Plastic ampoule 生化/生理作用 Target IC50: 18.3 nM inhibiting Ca2+ currents in adult rat cervical ganglion in a reversible and dose-dependent manner
Primary Target
Ca2+ currents in adult rat cervical ganglion in a reversible and dose-dependent manner
Product does not compete with ATP.
Cell permeable: no
Reversible: yes 警告 Toxicity: Standard Handling (A) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 其他说明 Phillips, R.M., and Altschuld, R.A. 1996. Biochem. Biophys. Res. Commun.229, 154.
Sellin, L.C., and McArdle, J.J. 1994. Pharmacol. Toxicol.74, 305.
Zhu, Y., and Ikeda, S.R. 1993. Neurosci.Lett. 155, 24. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息 | 经验(实验)分子式 | C4H7NO2 | | 分子量 | 101.10 | | MDL编号 | MFCD00002116 |
产品性质 | 质量水平 | 100 | | 测定 | ≥98% (GC) | | 形式 | solid | | manufacturer/tradename | Calbiochem® | | 储存条件 | OK to freeze
desiccated (hygroscopic) | | 颜色 | white to off-white | | 溶解性 | methanol: 100 mg/mL | | 运输 | ambient | | 储存温度 | 2-8℃ | | InChI | 1S/C4H7NO2/c1-3(5-7)4(2)6/h7H,1-2H3/b5-3+ | | InChI key | FSEUPUDHEBLWJY-HWKANZROSA-N |
安全信息 | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
|
| 099089 | Fluorochem | 2,3-Butanedione monoxime | >98% | 220元/1g; 330元/10g; 638元/25g; | 咨询 |
基本信息 | CAS Number | 57-71-6 | | MDL Number | MFCD00002116 |
安全信息 | 图形或危害标志 |  | | 危险性说明 | H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
|
|
m.cnreagent.com