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CAS: 57-67-0
分子式: C7H10N4O2S
分子量: 214.24
熔点: 185-189℃
中文名称: 
磺胺脒
磺胺胍
磺酰胍
克痢定
匡乃定
对氨基苯磺酰胍
氨苯磺酰胍
英文名称: 
4-Amino phenylsulfonyl guanidine
SULFAGUANDINE
SG
n(sup 1)-amidino-sulfanilamid
4-amino-n-(aminoiminomethyl)benzenesulfonamide
4-amino-n-(diaminomethylene)benzenesulfonamide
abiguanil
aterian
4-amino-n-(aminoiminomethyl)-benzenesulfonamid
4-amino-n-(diaminomethylene)-benzenesulfonamid
ganidan
guamide
guanicil
guanidan
sulfanilyl-guanidin
n(sup 1)-(diaminomethylene)sulfanilamide
n(sup 1)-amidinosulfanilamide
n(sup 1)-guanylsulfanilamide
n-p-aminobenzenesulphonylguanidine monohydrate
p-aminobenzenesulfonylguanidine
resulfon
rp 2275
ruocid
shigatox
suganyl
sulfaguanidine
sulfaguine
sulfanilguanidine
sulfanilylguanidine
sulfoguanidine
sulfoguenil
sulfoquanidine
sulgin
sulphaguanidine
展开更多英文名
性质描述: 白色针状结晶性粉末。熔点190-193℃,1g溶于约1000ml25℃的水,溶于约10ml100℃水。微溶于乙醇或丙酮,易溶于稀盐酸。无臭,无味,遇光色渐变深。
生产方法: 磺胺与硝酸胍缩合而得。
用途: 磺胺类药物,用于细菌性痢疾、肠炎等。
推荐供应商
货号品牌产品名称规格包装、参考价格
S797886MACKLIN磺胺胍10mM in DMSO186元/1ml;   咨询
储存:-20°C
状态:白色至灰白色粉末
S817736MACKLIN磺胺胍98%30元/25g;   49元/100g;   158元/500g;   778元/2.5kg;   咨询
储存:室温
状态:白色至灰白色粉末
S0464TCISulfaguanidine>98.0%(T)(HPLC)195元/25G;   1060元/500G;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C7H10N4O2S = 214.24
外观与形状(20℃)固体
Reaxys-RN747716
PubChem物质ID87575945
Merck Index (14)8908
MDL编号MFCD00038136

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %(calcd.on anh.substance)
Melting point187.0 to 191.0 ℃
Solubility in hot Wateralmost transparency
Water7.5 to 8.1 %

物性(参考值)

熔点189 ℃
水溶性实际上不溶
溶解性(微溶于)
溶解性(不溶于)乙醚

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#WO8575000
167951J&KSulfaguanidine99%166元/25G;   429元/100G;   咨询

基本信息

分子式C7H10N4O2S
分子量214.24
MDL编码MFCD00038136
Beilstein2695326
EINECS 编号200-345-9

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSWO8575000
C43130Alfa AesarSulfaguanidine98%539元/25g;   1017元/100g;   3753元/500g;   咨询

基本信息

Ref#
43130

MDL
38136

分子式
C7 H10 N4 O2 S

分子量
214.25

R10858Alfa AesarSulfaguanidine Standard solution100ppm210元/1ml;   咨询

安全信息

危险等级
3

S1975600SulfaguanidineEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 60 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C7H10N4O2S
分子量214.24
Beilstein2695326
MDL编号MFCD00038136
PubChem化学物质编号329824499
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringNC(=N)NS(=O)(=O)c1ccc(N)cc1
InChI1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)
InChI keyBRBKOPJOKNSWSG-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
S8751Sigma-AldrichSulfaguanidine466.87元/25 G;   咨询

产品说明

一般描述

化学结构:磺胺

包装

25, 100, 500 g in poly bottle

应用

磺胺胍被用来阻止叶酸的合成。可用于研究其对微孢子生长和宿主细胞活力的影响。

生化/生理作用

磺胺胍是一种磺胺类抗生素。磺酰胺可通过抑制二氢蝶呤合酶来阻止二氢叶酸的合成。磺胺类药物是细菌对氨基苯甲酸(PABA;细菌中叶酸合成所必需)的竞争性抑制剂。磺胺胍是一种二氢叶酸还原酶(DHFR)的抑制剂。磺胺类药物对革兰氏阳性细菌和革兰氏阴性细菌具有活性。抗性模式是通过二氢蝶呤合酶的改变或叶酸合成的替代途径。

其他说明

将容器密闭保存在干燥和通风良好的地方。在干燥处保存。储存类别 (TRGS 510):非易燃固体

基本信息

经验(实验)分子式C7H10N4O2S
分子量214.24
Beilstein2695326
EC 号200-345-9
MDL编号MFCD00038136
PubChem化学物质编号24899810
NACRESNA.85

产品性质

质量水平200
生物来源synthetic (Organic)
形式powder
颜色 white to off-white
溶解性1 M HCl: soluble 50 mg/mL
作用机制DNA synthesis | interferes
enzyme | inhibits
抗生素抗菌谱Gram-negative bacteria
Gram-positive bacteria
SMILES stringNC(=N)NS(=O)(=O)c1ccc(N)cc1
InChI1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)
InChI keyBRBKOPJOKNSWSG-UHFFFAOYSA-N
Gene Informationhuman ... F2(2147), PRSS1(5644)

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
32402SupelcoSulfaguanidineVETRANAL®, analytical standard775.33元/100 MG;   咨询

产品说明

一般描述

Chemical structure: sulfonamide
Sulfaguanidine belongs to the sulfonamide class of antibiotics. It can exhibit broad-spectrum inhibition of both gram-positive and gram-negative bacteria.

应用

Sulfaguanidine may be used as an analytical reference standard for the determination of sulfaguanidine in:

  • Food samples of animal origin by salting-out supported liquid extraction (SOSLE) and quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction followed by analysis using nanoflow liquid chromatography high resolution mass spectrometry (LC-HRMS).
  • Bovine muscle samples by hydrophilic interaction liquid chromatography-electrospray-tandem mass spectrometry (HILIC-ESI-MS/MS) equipped with selected reaction monitoring (SRM) mode of detection.
  • Tissues, milk and eggs of food producing animals by ultrasound-assisted extraction (UAE), solid phase extraction (SPE) and LC-MS/MS.
  • Beeswax by solid-liquid extraction (SLE), liquid-liquid extraction (LLE), SPE, QuEChERS extraction and ESI-LC-MS/MS with SRM detection.


Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C7H10N4O2S
分子量214.24
Beilstein2695326
EC 号200-345-9
MDL编号MFCD00038136
PubChem化学物质编号329754181
NACRESNA.24

产品性质

等级analytical standard
质量水平100
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)clinical testing
格式neat
SMILES stringNC(=N)NS(=O)(=O)c1ccc(N)cc1
InChI1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)
InChI keyBRBKOPJOKNSWSG-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
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