CAS 555-30-6; 左旋甲基多巴; alphamethyldopa

CAS:

555-30-6

分子式:

C10H13NO4

分子量:

211.21

沸点:

441.6ºC

熔点:

300℃

中文名称:

左旋甲基多巴

甲基多巴

L-3-(3,4-二羟基苯基)-2-甲基丙氨酸

L-甲基多巴

英文名称:

alphamethyldopa

amd

bayer 1440 l

baypresol

dopamet

methyl dopa

dopatec

dopegyt

l(-)-beta-(3,4-dihydroxyphenyl)-alpha-methylalanine

l-(-)-3-(3,4-dihydroxyphenyl)-2-methylalanine

l-(-)-alpha-methyl-beta-(3,4-dihydroxyphenyl)alanine

l-(alpha-md)

l-2-amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid

l-3-(3,4-dihydroxyphenyl)-2-methylalanine

l-alpha-methyl-3,4-dihydroxyphenylalanine

l-alpha-methyldopa

l-methyldopa

3-hydroxy- alpha-methyl-l-tyrosin

3-hydroxy-alpha-methyl-l-tyrosin

medomet

medopren

methoplain

methyldopa

mk 351

mk b51

nci-c55721

nr.c 2294

nrc 2294

presinol

presolisin

sedometil

sembrina

3-(3,4-dihydroxyphenyl)-2-methyl-l-alanine, sesquihydrate

l-3-(3,4-Dihydroxyophenyl)-2-methylalanine

3-Hydroxy-methyl-L-tyroxine

4-dihydroxyphenyl)-2-methyl- 3-( l-(-)-alanin

(-)-methyldopa

3-hydroxy-alpha-methyl-l-tyrosine

aldomet

aldometil

aldomin

alpha medopa

alpha-methyl dopa

alpha-methyl-beta-(3,4-dihydroxyphenyl)-l-alanine

alpha-methyl-dopa

alpha-methyl-l-3,4-dihydroxyphenylalanine

alpha-methyl-l-dopa

alpha-methyldopa

l-alpha-methyldop

展开更多英文名

性质描述:

白色结晶。熔点306-307℃（融化时分解），可溶于热水、稀酸和稀碱、微溶于冷水和丙酮等有机溶剂。

用途:

左旋甲基多巴是一种β-受体阻滞型心血管药物,对中等程序的原发性和肾性高血压有良好疗效。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

M769242

MACKLIN

甲基多巴

≥98.0%

199元/5g; 560元/25g;

咨询

储存：室温,干燥,密封
状态：白色到几乎白色粉末到晶体
物化性质：粉末
折射率：-14 °(C=1, H2O)

D1817

TCI

3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine Sesquihydrate

>98.0%(T)(HPLC)

655元/5G; 1870元/25G;

咨询

基本信息

纯度/分析方法	>98.0%(T)(HPLC)
分子式/分子量	C₁₀H₁₃NO₄・1^^₁/2H₂O = 238.24
外观与形状(20℃)	固体
储存在惰性气体下	存放于惰性气体之中
应避免的情况	光,空气
相关CAS RN	41372-08-1
Reaxys-RN	2807721
PubChem物质ID	87568286
Merck Index (14)	6055
MDL编号	MFCD00004186

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(Nonaqueous Titration)	min. 98.0 %(calcd.on anh.substance)
Specific rotation [a]20/D	-12.5 to -14.5 deg(C=1, H2O)
Solubility in hot Water	almost transparency
Water	10.0 to 12.0 %

物性(参考值)

比旋光度 [α]D

-14° (C=1,H2O)

安全信息

信号词	警告
危险性说明	H303 : 吞咽可能有害。
防范说明	P312 : 如感觉不适，呼叫急救中心/医生。

相关法规

RTECS#

AY5950000

329925

J&K

Methyldopa Sesquihydrate

98%, 一种α2-肾上腺素受体选择性激动剂

428元/1G; 1409元/5G;

咨询

基本信息

分子式	C₁₀H₁₃NO₄·1/2H₂O
分子量	211.22 (Anhydrous)
沸点	441.6
闪点	220.9
密度	1.403
比旋光度([α]20D)	-14.5° to -12.5° (C=1, H2O)
MDL编码	MFCD00004186
Beilstein	2807721
Merck	14,6055
存储条件	Freezer -20℃

产品描述

Methyldopa 是DOPA 脱羧酶竞争性抑制剂，ED50为21.8 mg/kg。

靶点（IC50 & Targe）

DOPA decarboxylase,21.8mg/kg(ED50)

参考文献

[1] DAY MD, et al. Br J Pharmacol Chemother. 1964, 22:72-86.

安全信息

图形或危害标志
提示语	Warning
危险说明	H303
防范说明	P312
WGK	3
RTECS	AY5950000

240920

Fluorochem

(S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid sesquihydrate

95%

968元/5g; 2838元/25g;

咨询

基本信息

CAS Number	555-30-6
MDL Number	MFCD00004186

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .