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CAS: 55079-83-9
分子式: C21H26O3
分子量: 326.40
熔点: 228-230 °C
中文名称: 
阿曲汀
阿维A酸
芳香维A酸
英文名称: 
6,8-nonatetraenoic acid, 3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-4
(all-e)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatet raen
acitretin
(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-nona-2,4,6,8-tetraenoic acid
all-trans-3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonat etra
all-trans-etretin
etretin
neotigason
retinoid etretin
ro 10-1670
soriatane
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格
A800202MACKLIN阿曲汀98%49元/25mg;   75元/100mg;   咨询
储存:2~8°C
状态:白色到浅黄色粉末
A795375MACKLIN阿曲汀10mM in DMSO525元/1ml;   咨询
储存:-20°C
A3097TCIAcitretin>98.0%(T)(HPLC)300元/50MG;   995元/250MG;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C21H26O3 = 326.44
外观与形状(20℃)固体
储存温度<0℃
储存在惰性气体下存放于惰性气体之中
应避免的情况光,空气,加热
包装和容器 250MG-带有塑料内管的玻璃瓶 (查看图片),  50MG-带有塑料内管的玻璃瓶 (查看图片)
Reaxys-RN2158933
PubChem物质ID354335416
Merck Index (14)112
MDL编号MFCD00866632

技术规格

AppearanceLight yellow to Yellow to Green powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %

物性(参考值)

熔点230 ℃
最大吸收波长352(MeOH) nm

安全信息

图形或危害标志
信号词危险
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H360 : 可能对生育能力或胎儿造成伤害。
H410 : 对水生生物毒性极大并具有长期持续影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P391 : 收集溢出物。
P308 + P313 : 如接触到或有疑虑:求医/就诊。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P405 : 存放处须加锁。

运输信息

UN编号UN3077
类别9
包装类别 III
监管条件代码(*)
208751J&KAcitretin98%285元/50MG;   945元/250MG;   咨询

基本信息

分子式C21H26O3
分子量326.44
熔点230
MDL编码MFCD00866632
Beilstein2158933
Merck14112
存储条件Store at 0℃

安全信息

图形或危害标志
提示语Danger
危险说明H315
H319
H360
H410
防范说明P273
P202
P201
P264
P280
P302+P352
P391
P308+P313
P337+P313
P305+P351+P338
P362+P364
P332+P313
P405
UN号码3077
危险分类9
包装等级III
C46644Alfa AesarAcitretin8872元/1g;   27173元/5g;   咨询

基本信息

Ref#
46644

分子式
C21H26O3

分子量
398.34

GHS危害和防范说明

Hazard Statements
H315 H319 H360 H410

Precautionary Statements
P302+P352 P332+P313 P305+P351+P338 P280 P308+P313

安全信息

危险等级
9

A0225000AcitretinEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs).

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H26O3
分子量326.43
MDL编号MFCD00866632
PubChem化学物质编号329770586
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCOc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C
InChI1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
InChI keyIHUNBGSDBOWDMA-AQFIFDHZSA-N
Gene Informationhuman ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H315 - H319 - H360 - H410
预防措施声明P201 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
44707Sigma-AldrichAcitretin≥98.0% (HPLC)1227.95元/25 MG;   咨询

产品说明

应用

Acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis.

生化/生理作用

Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs).

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 44707.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式C21H26O3
分子量326.43
EC 号259-474-4
MDL编号MFCD00866632
PubChem化学物质编号57650239
NACRESNA.25

产品性质

质量水平100
测定≥98.0% (HPLC)
形式powder
SMILES stringCOc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C
InChI1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
InChI keyIHUNBGSDBOWDMA-AQFIFDHZSA-N
Gene Informationhuman ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H315 - H319 - H360 - H410
预防措施声明P201 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Y0001987Acitretin for impurity A identificationEuropean Pharmacopoeia (EP) Reference Standard1259.15元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs).

包装

Unit quantity: 5 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H26O3
分子量326.43
EC 号259-474-4
MDL编号MFCD00866632

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
格式neat
储存温度2-8℃
SMILES stringCOc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C
InChI1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
InChI keyIHUNBGSDBOWDMA-AQFIFDHZSA-N
Gene Informationhuman ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H315 - H319 - H360 - H410
预防措施声明P201 - P264 - P273 - P280 - P308 + P313 - P391
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP827AcitretinBritish Pharmacopoeia (BP) Reference Standard1861.35元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs).

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H26O3
分子量326.43
EC 号259-474-4
MDL编号MFCD00866632
NACRESNA.24

产品性质

等级pharmaceutical primary standard
保质期limited shelf life, expiry date on the label
manufacturer/tradenameBP
格式neat
储存温度−20℃
SMILES stringCOc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C
InChI1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
InChI keyIHUNBGSDBOWDMA-AQFIFDHZSA-N
Gene Informationhuman ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H315 - H319 - H360 - H410
预防措施声明P201 - P280 - P305 + P351 + P338 - P308 + P313
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1011007USPAcitretinUnited States Pharmacopeia (USP) Reference Standard7584.83元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Synthetic retinoid that is a metabolite of etretinate. Preferentially binds to cellular retinoic acid binding proteins (CRABPs).

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C21H26O3
分子量326.43
MDL编号MFCD00866632
PubChem化学物质编号329748897
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCOc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C
InChI1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
InChI keyIHUNBGSDBOWDMA-AQFIFDHZSA-N
Gene Informationhuman ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H315 - H319 - H360 - H410
预防措施声明P201 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9
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