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CAS: 5466-84-2
分子式: C8H3NO5
分子量: 193.12
沸点: 197 °C
熔点: 117-118℃
中文名称: 
4-硝基苯二甲酸酐
4-硝基酞酐
4-硝基邻苯二甲酸酐
英文名称: 
4-Nitro-1,2-benzenedicarboxylic acid anhydride
4-nitro-phthalic anhydrid
5-nitro-3-isobenzofurandione
4-nitrophthalic acid anhydride
4-nitrophthalic anhydride
5-nitro-1,3-isobenzofurandione
性质描述: 无色或灰黄色针状结晶。熔点119℃。溶于热醇、热乙酸和丙酮,不溶于水。
生产方法: 由4-硝基苯二甲酰亚胺水解生成4-硝基邻苯二甲酸(610-27-5),再经脱水而得。将4-硝基苯二甲酰亚胺加入氢氧化钠溶液,加热沸腾15min。用硝酸调整pH6-8,再加硝酸沸腾5min。冷却,过滤,滤液用乙醚提取,提取液经干燥后蒸去乙醚,即析出4-硝基苯二甲酸酐晶体。收率95%。
用途: 用作荧光染料异硫氰酸荧光素的中间体,也用于测定醇类。
推荐供应商
货号品牌产品名称规格包装、参考价格
N831959MACKLIN4-硝基邻苯二甲酸酐98%26元/5g;   64元/25g;   200元/100g;   990元/500g;   咨询
储存:室温
状态:灰色到棕褐色到棕色粉末
折射率:1.585
N0246TCI4-Nitrophthalic Anhydride>98.0%(GC)1675元/25G;   3930元/100G;   咨询

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C8H3NO5 = 193.11
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (分解)
Reaxys-RN179682
PubChem物质ID87573607
SDBS (AIST Spectral DB)1006
MDL编号MFCD00005922

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(GC)min. 98.0 %
Purity(Methanolysis Method)min. 97.0 %
Melting point117.0 to 122.0 ℃

物性(参考值)

熔点120 ℃
沸点197 ℃/8 mmHg

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#TI3328000
238505J&K4-Nitrophthalic Anhydride93%332元/5G;   咨询

基本信息

分子式C8H3NO5
分子量193.11
熔点116-120
MDL编码MFCD00005922
Beilstein179682
EINECS 编号226-776-2

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSTI3328000
L08020Alfa Aesar4-Nitrophthalic Anhydridetech. 90%867元/5g;   4316元/25g;   咨询

应用
4-Nitrophthalic anhydride is used an an intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472).

备注
Moisture Sensitive. Store away from strong bases and oxidizing agents. Incompatible with water, bases, strong acids and oxidizing agents.

基本信息

MDL
MFCD00005922

EINECS
226-776-2

分子式
C8H3NO5

分子量
193.11

熔点
116-121°

灵敏度
Moisture Sensitive. Ambient temperatures.

溶解性
Hydrolyzes in water.

Beilstein
179682

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
TI3328000

TSCA

161000Fluorochem4-Nitrophthalic Anhydride97%220元/1g;   506元/5g;   1826元/25g;   4950元/100g;   咨询

基本信息

CAS Number5466-84-2
MDL NumberMFCD00005922
Melting Point118-120℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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