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CAS: 54-42-2
分子式: C9H11IN2O5
分子量: 354.12
熔点: 155-180℃
中文名称: 
碘甘
疱疹净
碘去氧啶
5-碘代-2'-脱氧尿嘧啶核苷
2'-脱氧-5-碘-尿核苷
5-碘-2'-去氧尿核苷
碘脱氧脲啶
5-碘-2'-脱氧尿嘧啶核苷
5'-碘脱氧脲嘧啶核苷
5'-碘-2-去氧尿核苷
2-脱氧-5'-碘尿核苷
碘苷
5-碘-2'-脱氧尿苷
展开更多中文名
英文名称: 
allergan 211
dendrid
emanil
herpesil
herpidu
herplex
herplex liquifilm
idexur
idoxene
idoxuridin
idoxuridine
idu
iducher
idulea
iduoculos
idur
iduridin
iudr
joddeoxiuridin
kerecid
nsc 39661
ophthalmadine
sk&f 14287
stoxil
synmiol
2'-deoxy-5-iodo-uridin
(+)-5-iodo-2'-deoxyuridine
5-Indo-2'-deoxyuridine
1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil
5-Iododesoxyuridine
1-(2-deoxy-beta-d-ribofuranosyl)-5-iodouracil
1-beta-d-2'-deoxyribofuranosyl-5-iodouracil
2'-deoxy-5-iodouridine
5-iodo-2'-deoxyuridine
5-iododeoxyuridine
5-iodouracil deoxyriboside
5iudr
展开更多英文名
性质描述: 白色或类白色结晶性粉末。熔点190-195℃（分解）。极微溶于水，几乎不溶于氯仿、乙醚，微溶于乙醇、丙酮。在酸性水溶液中稳定，溶液遇光及高压灭菌时被分解。
生产方法: 有多种生产方法。从丙炔醇开始，经氧化、酯化，再与2-氨基噁唑啉核苷环合可得2,2-氧桥嘧啶核苷，然后经酰化、溴化、催化氢化、水解得到碘苷。从鱼精可以制取5'-脱氧胞嘧啶核苷酸，经进一步加工亦可制得碘苷。
用途: 抗病毒药，用于单纯疱疹角膜炎和疱疹脑炎等。
推荐供应商
货号品牌产品名称规格包装、参考价格
I796242MACKLIN5-碘-2'-脱氧尿苷10mM in DMSO185元/1ml;   咨询
储存：-20°C
I811619MACKLIN5-碘-2'-脱氧尿苷99%38元/1g;   165元/5g;   672元/25g;   2265元/100g;   咨询
储存：室温,干燥,密封
状态：白色到灰白色粉末或晶体
折射率：30 ° (C=1, 1mol/L NaOH)
I0258TCI5-Iodo-2'-deoxyuridine>99.0%(T)540元/1G;   1720元/5G;   6590元/25G;   咨询

基本信息

纯度/分析方法>99.0%(T)
分子式/分子量C9H11IN2O5 = 354.10
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况光,空气
Reaxys-RN30397
PubChem物质ID87571623
SDBS (AIST Spectral DB)4820
Merck Index (14)4891
MDL编号MFCD00134656

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 99.0 %
Specific rotation [a]20/D+28.0 to +31.0 deg(C=1, 1mol/L NaOH sol.)
Solubility in hot Wateralmost transparency

物性(参考值)

比旋光度 [α]D30° (C=1,1mol/L NaOH sol.)

安全信息

图形或危害标志
信号词警告
危险性说明H302 + H312 + H332 : 吞咽、皮肤接触或吸入有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H361 : 怀疑对生育能力或胎儿造成伤害。
H341 : 怀疑可造成遗传性缺陷。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P271 : 只能在室外或通风良好之处使用。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P308 + P313 : 如接触到或有疑虑：求医/就诊。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。
P302 + P352 + P312 : 如皮肤沾染：用水充分清洗。如感觉不适，呼叫急救中心/医生。
P304 + P340 + P312 : 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。如感觉不适，呼叫急救中心/医生。
P405 : 存放处须加锁。

相关法规

RTECS#YU7700000
139450J&K5-Iodo-2'-deoxyuridine95%, 猫科1型疱疹抗病毒剂284元/1G;   1115元/5G;   咨询

基本信息

分子式C9H11IN2O5
分子量354.10
熔点194
MDL编码MFCD00134656
Merck14,4891
EINECS 编号200-207-8
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
H341
H361
防范说明P261
P281
P305+P351+P338
WGK3
RTECSYU7700000
TSCA是
A11542Alfa Aesar(+)-5-Iodo-2'-deoxyuridine98%1380元/1g;   5569元/5g;   咨询

基本信息

MDL
MFCD00134656

EINECS
200-207-8

分子式
C9H11IN2O5

分子量
354.10

熔点
ca 190° dec.

形态
Crystalline powder

Beilstein
30397

Merck
14,4891

GHS危害和防范说明

GHS符号

Hazard Statements
H351-H361
Suspected of causing cancer.Suspected of damaging fertility or the unborn child.

Precautionary Statements
P201-P280-P202-P308+P313-P405-P501a
Obtain special instructions before use.Wear protective gloves/protective clothing/eye protection/face protection.Do not handle until all safety precautions have been read and understood.IF exposed or concerned: Get medical advice/attention.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
40-63
Limited evidence of a carcinogenic effect.Possible risk of harm to the unborn child.

安全等级
36/37
Wear suitable protective clothing and gloves.

欧盟危险品标志

RTECS
YU7700000

TSCA
是

1336001USPIdoxuridineUnited States Pharmacopeia (USP) Reference Standard4682.6元/250 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C9H11IN2O5
分子量354.10
Beilstein30397
MDL编号MFCD00134656
PubChem化学物质编号329750148
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp194 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringOC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O
InChI1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI keyXQFRJNBWHJMXHO-RRKCRQDMSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341 - H361
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
I0050000IdoxuridineEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C9H11IN2O5
分子量354.10
Beilstein30397
MDL编号MFCD00134656
PubChem化学物质编号329815294
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp194 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O
InChI1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI keyXQFRJNBWHJMXHO-RRKCRQDMSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341 - H361
预防措施声明P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
I7125Sigma-Aldrich5-Iodo-2′-deoxyuridine≥99% (HPLC)4183.57元/5 G;   16642.3元/25 G;   咨询

产品说明

应用

5-Iodo-2′-deoxyuridine has been used in molecular combing assay or DNA fiber assay.
5-碘-2′-脱氧尿苷(5-IUdR；IdUrd)是一种嘧啶类似物(卤代胸苷)，具有抗牛痘病毒(正痘病毒)活性。 IdUrd在人类癌症研究中被用作放射增敏剂。

包装

5, 25 g in glass bottle

生化/生理作用

5-Iodo-2′-deoxyuridine prevents in vitro DNA viral replication. This is observed in herpesviruses and poxviruses It might possess teratogenic, tumor-promoting, mutagenic, and immunosuppressive properties. 5-Iodo-2′-deoxyuridine, used in topical applications, is effective against epithelial infections.

基本信息

经验(实验)分子式C9H11IN2O5
分子量354.10
Beilstein30397
EC 号200-207-8
MDL编号MFCD00134656
PubChem化学物质编号57654307
NACRESNA.51

产品性质

质量水平200
测定≥99% (HPLC)
形式powder or crystals
mp194 ℃ (lit.)
溶解性1 N NH4OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow
储存温度2-8℃
SMILES stringOC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O
InChI1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI keyXQFRJNBWHJMXHO-RRKCRQDMSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341 - H361
预防措施声明P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
PHR2884SupelcoIdoxuridinepharmaceutical secondary standard, certified reference material3340.09元/500 mg;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

基本信息

经验(实验)分子式C9H11IN2O5
分子量354.10
Beilstein30397
MDL编号MFCD00134656

产品性质

等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
mp194 ℃ (lit.)
application(s)pharmaceutical
药典可追溯性traceable to BP BP202
traceable to USP 1336001
储存温度2-30℃
SMILES stringOC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O
InChI1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI keyXQFRJNBWHJMXHO-RRKCRQDMSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341 - H361
预防措施声明P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP202IdoxuridineBritish Pharmacopoeia (BP) Reference Standard2217.2元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C9H11IN2O5
分子量354.10
Beilstein30397
MDL编号MFCD00134656

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
mp194 ℃ (lit.)
格式neat
储存温度2-8℃
SMILES stringOC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O
InChI1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI keyXQFRJNBWHJMXHO-RRKCRQDMSA-N

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341 - H361
预防措施声明P201 - P261 - P264 - P280 - P304 + P340 + P312 - P308 + P313
危险分类Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
092965Fluorochem5-Iodo-2'-deoxyuridine95%220元/1g;   880元/5g;   1430元/10g;   3102元/25g;   咨询

基本信息

CAS Number54-42-2
MDL NumberMFCD00134656
Melting Point194 ℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H341: Suspected of causing genetic defects ..
H361: Suspected of damaging fertility or the unborn child ..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P281: Use personal protective equipment as required.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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