| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |
| D838212 | MACKLIN | 1-(2,6-二甲基苯氧基)-2-丙胺 盐酸盐, 97% | 97 % | 89元/5g; 235元/25g; | 咨询 |
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| D793377 | MACKLIN | 1-(2, 6-二甲基苯氧基)-2-丙胺 盐酸盐, 97% | 10mM in DMSO | 311元/1ml; | 咨询 |
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| M2040 | TCI | Mexiletine Hydrochloride | >98.0%(HPLC)(N) | 345元/1G; 1015元/5G; | 咨询 |
基本信息 | 纯度/分析方法 | >98.0%(HPLC)(N) | | 分子式/分子量 | C11H17NO・HCl = 215.72 | | 外观与形状(20℃) | 固体 | | Reaxys-RN | 4209895 | | PubChem物质ID | 87560985 | | SDBS (AIST Spectral DB) | 52401 | | Merck Index (14) | 6169 | | MDL编号 | MFCD00216024 |
技术规格 | Appearance | White to Almost white powder to crystal | | Purity(HPLC) | min. 98.0 area% | | Purity(with Total Nitrogen) | min. 98.0 % | | Melting point | 200.0 to 205.0 ℃ |
物性(参考值) | 熔点 | 202 ℃ | | 最大吸收波长 | 272(MeOH) nm | | 水溶性 | 完全溶解 | | 溶解性(易溶于) | 醇 |
安全信息 | 图形或危害标志 |  | | 信号词 | 警告 | | 危险性说明 | H302 : 吞咽有害。 H315 : 造成皮肤刺激。 H319 : 造成严重眼刺激。
| | 防范说明 | P501 : 将内装物/容器送到批准的废物处理厂处理。 P270 : 使用本产品时不要进食、饮水或吸烟。 P264 : 作业后彻底清洗皮肤。 P280 : 戴防护手套/戴防护眼罩/戴防护面具。 P302 + P352 : 如皮肤沾染:用水充分清洗。 P337 + P313 : 如仍觉眼刺激:求医/就诊。 P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。 P332 + P313 : 如发生皮肤刺激:求医/就诊。 P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
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相关法规 |
| C37291 | Alfa Aesar | Mexiletine Hydrochloride | | 514元/5g; 1440元/25g; 4685元/100g; | 咨询 |
基本信息 Ref# 37291 分子式 C11H17NO.HCl 分子量 123.89 GHS危害和防范说明 GHS符号
 Hazard Statements H302 H315 H319 Precautionary Statements P301+P330+P331 P312 P302+P352 P337+P313 P280 |
| M2727 | Sigma-Aldrich | Mexiletine Hydrochloride | powder | 1468.97元/25 G; 3943.82元/100 G; | 咨询 |
产品说明 一般描述 美西律是一种IB类抗心律失常药,是利多卡因的类似物。它的半衰期为10-12小时,在肝脏中代谢,通过还原、氧化或结合反应消除。 应用 盐酸美西律可作为钠离子通道阻滞剂用于:
- 中国仓鼠卵细胞
- 人胚胎肾 (HEK) 细胞,用于全细胞膜片钳研究
- 表达Nav1.7蛋白的HEK细胞的电生理研究
生化/生理作用 美西律是一种有效的钠离子通道阻滞药。它是一种抗心律失常药,在头疼和神经性疼痛中可作为辅助药物美西律用于治疗钠离子通道病的肌强直症状,并缩短心脏动作电位的去极化时程,但不会对心房不应期造成影响。它对钠通道的抑制作用可有效治疗钾加重性肌强直。 特点和优势 该化合物由 Boehringer Ingelheim 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单,请单击此处。 基本信息 | 经验(实验)分子式 | C11H17NO · HCl | | 分子量 | 215.72 | | EC 号 | 250-825-7 | | MDL编号 | MFCD00216024 | | PubChem化学物质编号 | 24278542 | | NACRES | NA.77 |
产品性质 | 质量水平 | 200 | | 测定 | ≥98% (GC) | | 形式 | powder | | 颜色 | white to off-white | | 溶解性 | methanol: 50 mg/mL | | 创始人 | Boehringer Ingelheim | | 储存温度 | 2-8℃ | | SMILES string | Cl[H].CC(N)COc1c(C)cccc1C | | InChI | 1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H | | InChI key | NFEIBWMZVIVJLQ-UHFFFAOYSA-N | | Gene Information | human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) |
安全信息 | 象形图 |  | | 警示用语: | Warning | | 危险声明 | H302 | | 预防措施声明 | P264 - P270 - P301 + P312 - P501 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| M1860000 | | Mexiletine Hydrochloride | European Pharmacopoeia (EP) Reference Standard | 1259.15元/ ; | 咨询 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. 包装 Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. 注意 Please find SDS provided by EDQM here.. 其他说明 Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C11H17NO · HCl | | 分子量 | 215.72 | | MDL编号 | MFCD00216024 | | PubChem化学物质编号 | 329817898 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | EDQM | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | 储存温度 | 2-8℃ | | SMILES string | Cl[H].CC(N)COc1c(C)cccc1C | | InChI | 1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H | | InChI key | NFEIBWMZVIVJLQ-UHFFFAOYSA-N | | Gene Information | human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) |
安全信息 | 象形图 |  | | 警示用语: | Warning | | 危险声明 | H302 | | 预防措施声明 | P301 + P312 + P330 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 1443250 | USP | Mexiletine Hydrochloride | United States Pharmacopeia (USP) Reference Standard | 3231.47元/200 MG; | 咨询 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. 分析说明 These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. 其他说明 USP issued SDS can be found here. Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C11H17NO · HCl | | 分子量 | 215.72 | | MDL编号 | MFCD00216024 | | PubChem化学物质编号 | 329750463 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | USP | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | SMILES string | Cl[H].CC(N)COc1c(C)cccc1C | | InChI | 1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H | | InChI key | NFEIBWMZVIVJLQ-UHFFFAOYSA-N | | Gene Information | human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) |
安全信息 | 象形图 |  | | 警示用语: | Warning | | 危险声明 | H302 | | 预防措施声明 | P301 + P312 + P330 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 333722 | Fluorochem | MEXILETINE HCL | 95% | 374元/1g; 1100元/5g; 5038元/25g; 12562元/100g; | 咨询 |
基本信息 | CAS Number | 5370-01-4 | | MDL Number | MFCD00216024 |
安全信息 | 图形或危害标志 |  | | 危险性说明 | H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .
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